Yeah, I think the the condition of Luna's skin or her immune system is the problem rather than the antibiotic not working. Each time, the Simplicef has done what it is supposed to as far as clearing the infection, and this last time we continued the med for two full weeks after seeing the last active lesion. But Luna can't permanently stay on antibiotics, and there is always going to be staph naturally returning to her skin. But how to keep it from over-colonizing....?

I treated the spot with topicals yesterday and gave her another full bath today. I realize I was being unrealistic in hoping we'd never see another spot . Obviously there is something abnormal at the root of this, and unless we can figure that out we will just be trying to minimize the outbreaks. So I guess we will see over the next week or so whether at least we can keep a lid on things by using the topicals or instead whether the infection really breaks through in multiple areas again. If it does, I think I will press for trying the innoculation injections, although I think the protocol for that requires another six weeks of antibiotics in conjunction <SIGH>

One good thing is that Luna does not seem to mind her baths. I guess it feels like a nice warm puppy massage to her. So I am trying to make them be nice, happy times for the two of us to share together. The shampoo has to stay on for ten minutes, so I tell her what a good girl she is and sing little songs to her. She really IS such a good girl to put up with all of this.