When it comes to treament for Alivia, I am definitely between a rock and hard place. I have an e-mail from Dr. Oliver advising me against using Trilostane because it would increase her sex hormone levels and she would still exhibit all the symptoms of Cushing's
Sweetie, that is what Dr. Oliver told me about using Trilostane with Zoe. I turned to Dr. Peterson and he felt Zoe would be better off on the Trilostane. Dr. Peterson told me I should not even know about her intermediate hormones at that point. He felt the lysodren and her IBD would be a problem and with Trilostane I could start and stop the dose without worrying about losing a "load".

Point is, MB, we all make decisions and follow our heart with as much information as we can glean from the experts. My IMS gets frustrated because even the endocrinologists cannot agree.

I do wonder sometimes if the increase in macros we have seen is because of the increased usage of Trilostane. I think we would all prefer not to use either drug.

I am sorry Alivia's symptoms are coming back. I had Zoe on melatonin and lignans for quite a while before starting Trilostane. She was doing okay, not horrible symptoms except her coat and skin were getting worse and her back legs.

Her cortisol was sky high but her intermediates did come down. Dr. Oliver gave me the maintenance dose option too. You never know if it will work or not. I have read on other forums that dogs responded to that treatment without loading. Perhaps their cortsiol was not so high as Zoe's.

All we can do is try what we think best in our hearts.

love ya