Hello Marianne and Lori,

I just wanted to give an update since we've had some news. Joni's concerns have remained much the same since I wrote in, and we got a little vet fatigue and she wasn't getting worse so we just acquiesced for a time. But in February we took Joni for her standard physical, and her ALP came back high - in the 300s. The vet recommended rechecking this month. We just rechecked, and it's high again - this time higher - just shy of 400. Her ALT has gone up too, though still in the normal range she's jumped from usually being in the 40s to 94. She also has developed a new balding spot on the very tip of her tail, which is disconcerting to us, together with the other symptoms I shared before (drinking more, eating more, maybe peeing a bit more, darkening of her skin on her belly, and shedding). So, after some discussion, and though the levels aren't exceedingly high like other cush pups (I've read they can be over 1000??), the vet agreed that it's reasonable to do the LDDS testing.

So my questions are - do you ever see cush diagnosed with ALKP levels in the 300-400 range?
Any advice on what to consider relative to the LDDS testing / how to interpret results?

We are scheduling her after our next pay day, so she won't go back until March 26.

Finally, I am just curious - do you ever see behavioral impacts with cush? Joni has some anxiety based behaviors, and I'm just wondering if she does have cush, could it be making her more irritable?

Thank you in advance and hope you are well!

Shelton