Macroadenomas

[Iraklis]

Huskos' case would be much to difficult to put in one comment because most importantly ,apart from Cushings, it was a mixture of wrong diagnosis and poor Vetoryl follow ups and side-effects.

Here is the thread ,it makes for a long read i know...sorry...
http://www.k9cushings.com/forum/showthread.php?t=6211

I don't know for certain if it was related to Cushings ,but Husko was overweight for more than a year prior to noticing hind leg weakness...
It made me try to get him to lose weight by cycling (early 2013) since diet changes only helped very little...but stopped it due to him obviously not enjoying it.

Huskos' appetite had many ups&downs...during the summer while being treated with Medrol/Prezolon for (non-existant) ''athritis&liver'' cancer he lost his appetite.
During the 1st month of Vetoryl treatment he regained it...but lost it again during the 2nd month on 2*dose without ACTH test...(vets told me its a common side-effect & not to worry...told me the same when circling&pacing first appeared...would have avoided it all if i had signed up here and let people know, as i had discovered this forum...)
Re-gained appetite again during late-November ,9 days after the MRI and Vetoryl-stopping and 2 days after his first IV vit-C...
Lost it again during February to the end (immediately upon starting Vetoryl again...)
As Ginger said...it is a indicator something is wrong!

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My .02:
Once you suspect Cushings:
1.Get a liver biopsy to check for elevated corticosteroid signs if not certain of the cause of symptoms.
2.Get a belly ultrasound. Try to have a clear image of both adrenals
(In Huskos' case one of them was difficult to check ,so not knowing if Cushings was PDH or ADH caused many wrong decisions be made later on trying to be pre-cautious with money in case of Cushings being ADH & surgery needed).
3.Get a brain MRI (expensive but I guarantee it you won't regret it) ,followed by another one 2-6 months later or when possible, or if any of the following signs are observed (if during treatment of Vetoryl...STOP IT immediately...a macroadenoma causes much more serious damage & way quicker than elevated cortisol levels):
a.circling
b.pacing
c.can't drink water from bowl but rather ''licks'' the air above it
d.substantially decreased appetite