Vicki:
Yes Tipper had a rabies shot. She swelled up so big so fast I had an emergency vets within 8 minutes of my house then and we barely made it. She was starting with anaphylaxis by the time we got there. She had never had this particular vaccine form this company before. She had welts raised up on her as big a sausages, and her skin was so blown up she looked like a pig because she is so pink underneath her fur. I had to throw her in the vets sink in cool water as they got her a shot of epinephrine . Her mouth was swelled twice it's size. Her temperature went so high they told me any higher and she may not make it, I was hysterical, but held myself together and bathed her continuously for about 1/2 an hour in the sink. Finally the temperature started to come down. It was not a good day to say the least. It started within an hour of the vaccination. Hope some how this helps you. I did call the manufacturer and they took the info, but were not to forthcoming with any information as to why this happened or if other dogs reacted like this. Blessings
Patti