Hello! My name is Debbie and I am new to this group. This forum was recommended to me by a member of I Heart Senior Dogs. My fur baby is Sophie and she will be 14 in January. She is a Cocker Spaniel and Jack Russell mix and is a sweetheart. When we had her teeth cleaned this past summer the vet noted from her blood work that her liver enzmes were high. I do not have the test result but she said they were in the 900 range. She started Sophie on the Denamarin Advanced tablets. We gave her those for 3 months and went back for another blood test last week. The vet said her levels had come down slightly. They are now around 800, which she deemed way too high. She said the next step was a test for Cushings. I've read some negative things about how stressful this test can be for dogs and can result in positive results just because of the stress level they are under when tested. I want to do what is best for my puppy and I've heard this disease can be fatal if not treated. The main reason for the test is the high level enzymes. Sophie has had some nights when she gets up and wanders around the house, but those are far apart. She was panting a great deal but that seems to have greatly improved since she is on the Denamarin. She is not exhibiting excessive thirst and there has not been any change in her bathroom habits. She does have several skin tags now, but is not loosing hair. Help! I just want to do what is best for Sophie. If the test needs to be completed we will gladly have it done. Thanks so much for your help. It's just so difficult being entirely dependent upon your vet.