Hello All!
My dog Lucy, 11 1/2 year old shephard/lab mix, has had cushing's for about 2 years now, and been treated with trilostane. She's been pretty stable at 120 mg/day, 60 mg in the morning and 60 mg at night. However, over the past couple months her appetite started decreasing, so we had yet another stim test in February. Vet said her numbers were good, so to keep her at 60 and 60. Now she's hardly eating at all, has lost 20 lbs., (she's about 50 lbs now) is very lethargic, and seems to be in a drugged out state...i.e., standing and staring at a wall for long periods, no energy, depressed, very weak in her hind legs, almost like she's on a sedative.
I decided to stop the trilostane, her last dose was 60 mg. sunday morning....I have two vets now working on this. I'm afraid I'm losing her, and I can't stop crying. The vets told me to keep her off the trilo for a couple days, see if she bounces back. Has anyone else had this happen before? Good ACTH numbers, but clinically symptoms seem to be Addisonian? I'm hoping that's all it is, and she bounces back.
They're also telling me if she doesn't start eating we have to do another sonogram and more blood tests to rule out whatever. I hate to put her through the trauma of that right now. I've taken off from work now because I don't want to leave her....this is exhausting. Please someone tell me there's hope for her....thanks, Gina