Rosie has pituitary Cushing's — Rosie has crossed Rainbow Bridge

[FemaleK9]

Rosie's latest ACTH results:

Pre: 4.4 ug/dL
Post: 4.8 ug/dL

Since her symptoms are well controlled, she will stay at her original trilostane dosage, 10mg twice a day.

Full info:

Rosie’s ACTH tests (aka stim tests)

Measurement: ug/dL...........0718112..121114..12115..Ref Range*
Cortisol Sample 1 Pre (basal).... 5.8...... 4.1.......4.4......1.0 – 5.0
Cortisol Sample 2 Post Stim......6.3.......6.7.......4.8.......8 - 17


HAC (pre-treatment): Post ACTH results greater than 20 ug/dL (dog) are consistent with HAC

*Post Trilostane: Pre and post cortisol levels between 1.5 – 9.1 ug/dL indicate optimal control.

07/18/2013 After 14 days on Vetoryl (trilostane) 10 mg twice a day
12/11/2014 After 18 months on trilostane 10 mg twice a day
12/11/2015 After 2 yrs 6 mos on trilostane 10 mg twice a day (Wedgewood Pharmacy Gourmeds)

[Harley PoMMom]

Those stim numbers look fantastic!!! I am so happy to hear that dear Rosie is doing so well with her Trilostane treatment...another YAA!!! How's her anxiety?

Hugs, Lori

[FemaleK9]

Wose than ever, I'm afraid. I now have to sedate her every night. She starts to get anxious as soon as it gets dark, and goes into full blown panic as soon as I go to bed. I've tried everything I or the vet can think of to get away from the acepromazine, but it's the only thing that allows ME to get any sleep.

[Harley PoMMom]

I remember one of our members using Dog Appeasing Pheromone (DAP) with some success, I also ran across this article that lists some suggestions for dog anxiety, hopefully it will be of help: http://shibashake.com/dog/dog-anxiety-problems

Hugs, Lori

[molly muffin]

Oh poor Rosie, sorry she is still having bad anxiety. Melatonin doesn't help her?

That is a wonderful ACTH result btw. Congratulations.

[FemaleK9]

I just became aware of a new drug for dogs like my Rosie who have such a hard time with thunderstorms and all related phenomena.

Sileo from Zoetis

I am planning to ask Rosie's vet about it, but I know there are other dogs on here with the same problem, and I was wondering if anyone here has tried it on a cushpup?

[FemaleK9]

Okay, I guess not.


I sent an email to Rosie's vet today, asking her to lookm into it and give me advice. I'll post any updates here.

[DoxieMama]

My pups don't seem to be bothered by thunderstorms, so I don't have experience with that. But please do let us know what you find out as it may be helpful for others who do!

Shana

[molly muffin]

I'm sorry I meant to get back here and reply drat.

I did a search of the forum and didn't find anyone who has mentioned using or being told about SILEO/zoetis.

I also checked the facebook cushings group and couldn't find anything.

So if you do end up trying it, you will be a ground breaker for many whose dogs are fearful of so many things.

[FemaleK9]

That's what I figured, with it being so new. I did try searching the forum, too, so I knew there have been no posts about it yet.

The non-sedative feature really appeals to me, because I have had to use the acepromazine a lot lately and I hate that she has to be sedated to ease her fear.

I will update when I have a response from the vet.