New Member with 3 years of Cushings "cured" (Update: Macroadenoma)-Jackson has passed

[JacksonsMom]

Hello Everyone
I recall checking this site about 3 years ago, but I think it was closed to reopen later. Anyway, Jackson, my 12 year old Yorkie, was diagnosed in 2009 with Pituitary Cushings and treated successfully with Trilo during that time. His early symptoms were: first enlarged salivary glands, then hair loss, and finally pot belly. He was frequently rechecked during those three years and Trilo was adjusted according to the results of the ACTH test. In May and June his tests showed no more Cushings. Vet could not explain, but Jackson was becoming a finicky eater and losing weight (and eating dirt). They wanted to do liver biopsies, but treated him for Inflammatory Bowel Disease first (antibiotics). I sought a second opinion and was told I should get an MRI (Dr. Bruyette mentioned in the thread for Macroadenomas--tumors). I was reluctant because of the sedation required but we had the test on Friday and no surprise it showed a large tumor. I meet with him this coming Monday for Radiologists results and to discuss options: Surgery, Radiation, Clinical trials. I am so unhappy that the vet treating Jackson for Cushings never suggested an MRI, especially when his symptoms abated. I will post on the thread for Macroadenomas the results of our meeting. His current symptoms are tremors, anorexia, hair loss and elevated liver enzymes. He is on Prednisolone (2 mg twice a day from the first vet) to stimulate appetite and Dr. Bruyette is recommending a dose of 2.5 mg twice a day. My best wishes to everyone traveling down this road.

[Cyn719]

I am sorry for your bad news - we will pray for Jackson - I am now traveling that road - they think Penny might has a macro - she is going to be 12 in November - She hasnt felt well - some nights groaning - pacing - digging -- not sure - going to specialist on Wed - sending you strength and support - please keep us posted - all our prayers going out to you

[kapohotricia]

I'm so sorry that Jackson has a macro and, maybe, Penny too. My Kirby has all the signs too (tremors, circling, etc) though an MRI is not available in our remote rural area. It's comforting to see that macros don't seem to cause any pain and they don't know they are sick.

We started treating Kirby with Anipryl today. I have just posted to ask questions about that and maybe some answers to that thread will give you some helpful information. The members of this group are a wonderful resource and very kind to take time to share their knowledge.
Big hugs to you both, Penny and Jackson.
Aloha,
Tricia and Kirby

[ShannonJ92]

I'm sorry you are going through this with Jackson. I'm only learning my way around the ins and outs of Cushing's (newly diagnosed last month, I have a Yorkie too) and it's a really complicated disease. It's so tough, especially when other issues exist (believe me I know). Best of luck with your upcoming appt. and I hope that a treatment plan can be decided on to help your little Jackson. I'm so sorry he and you are going through this, keep us updated.

~Shannon

[Squirt's Mom]

Hi,

Welcome back to you and Jackson, tho I wish it was under better circumstances. You are right; the old site was shut down and this site started shortly after. Most of the old staff is still here as well as many members you may remember and a whole host of new folks. I glad you remembered us when your need arose and that we are still here to help.

There have been some fantastic advancements in treating macros over the last few years and I hope you will have some options that can bring both you and Jackson some relief and much more quality time together. Do let us know what you learn tomorrow and know we are here anytime you need to talk.

Keep your chin up!
Hugs,
Leslie and the gang

[JacksonsMom]

Thank you all for your kind words and support. There is comfort in knowing that our experiences will help others.
Warmest Regards,
Robin and Jackson

[JacksonsMom]

Just met with the vet and looked at the MRI. The tumor is 1.5 cm and looks huge. Dr said it is probably causing headaches (Jackson trembles seizure like even when sleeping).
Options are:
Do nothing and 1-3 months prognosis. I know it could be more, but with the headaches, what would be the quality of life?
Radiation: Daily for about a month, needing to be sedated every time.
Surgery: minimally invasive Vitol (here is a link: http://www.cedars-sinai.edu/About-Us...hance-Too.aspx)
Survival rate is 85% for 2 years or longer. (only been done on 10 dogs so far.) Since they remove the pitutary, he would be on thyroid, steroids and one other for hydration.
Both options cost about $8000. I don't know what I will do, but surgery seems the best option. I've already spent about $10,000 treating the Cushings for three years--I'm not rich by any measure, but as you will soon find out, each visit to check the ACTH is about $200-$400 and they always find something else that should be checked out. I'll let you know what I decide, and I'm going to start a thread on the Macro area for the rest of this ride.
My best to everyone
Robin

[frijole]

Robin, Please know you have all of us on your side and if there is anything we can do to lighten the load or help in any way - just let us know. Sending love and best wishes, Kim

[kapohotricia]

Hi Robin,
I'm so sorry to hear the results. Knowing what's best to do for our sick furkid when there are options is the hardest thing, isn't it? I do feel for you and pray you soon have peace with the choice you make. Give Jackson a gentle kiss from me and a big hug for you. My thoughts are with you.

Aloha,
Tricia and Kirby

[addy]

I just wanted to let you know I am thinking of you and sending prayers your way.

Love,
addy