Appreciate your input with Coopers experience. Irma’s “shivering” is so faint and sporadic too. I have learned that the scary adverse reaction would be a whole body/muscle tremor. Getting her dose dropped really low so we can get another ACTH test done is going to go a long way with her Cushings management.Her symptoms right this moment have been the increased water and urinating and the restlessness in the evening. She is on a single small dose now and we have seen a improvement in her personality and a slight improvement during the day with other symptoms. She’s a 12/13 year old black lab (guestimentvon age since she’s a rescue) about 70 lbs.