My sweet little mixed terrier Ellie who is 15 years old and weighs 16.5 lbs was diagnosed with cushings last week after displaying all the typical symptoms and having the ACH test. She also had a full blood panel and everything looked good except for slightly elevated liver enzymes. She was put on vetoryl 2xs a day 10mg morning and night which seemed high for her weight. After the first day she was fine but the second day after the night dose she could barely stand, was breathing heavy, was disoriented, and shaking. We held her thinking she was dying in our arms but after about an hour she has greatly improved. This was Friday night. The next morning she was much better and we decided not to give her the morning dose. We gave her the evening dose of 10mg. During the night she vomited in the middle of the night and in the morning she was extremely lethargic. This was now Sunday morning and we decided to skip the morning dose of 10mg again because she was barely eating. Sunday during the day she improved significantly and in the evening we gave her the evening dose of 10 mg. Monday morning was very lethargic again with no appetite so decided to hold off on the morning dose again. Monday night she was still was barely eating and had diarrhea so we gave her no meds except some antibiotics she has been on for a skin issue. This morning Tuesday she is still barely eating seems disoriented and still very lethargic. She has an appointment with the vet today and I pray we will get some answers. Ellie has been a very healthy dog her entire life up to a year ago when she had a soft cell malignant stage 2 tumor removed which has not returned and has not shown any indications that it has spread so I don’t think this related. We suspected Cushings because of the constant drinking, peeing, wandering around the house, incredible appetite, weakness in hind legs, etc. She was on proin for incognizance but that didn’t help much with the cushings peeing. My question is could she have gotten so sick so quickly from just a few of days of Vetoryl even after we lowered it?