Hi my dog a 12yo male bichon who weighs 22lb was diagnosed last year 8/19. It was confirmed pituitary induced Cushings after doing a sonogram to confirm. His symptoms were excessive drinking, hunger and would wake up mostly middle of night shaking and panting he did not have accidents in the house but the shaking and panting, pacing were most bothersome. He was put on vetoryl 30mgs. Seemed to reduce hunger and drinking. We have been monitoring and under control. This past week on two separate occasions he was up alll night panting shaking pacing like I have never seen before I even gave him Xanax and did not help. We bumped up amount to 40mgs and again last night same thing except now he is whimpering. We did blood work and liver enzymes are increasing over last few months. We found a nodule/tumor on liver when we did the sonogram but very small and we did recheck six month later no change in size. I give him cbd oil and have him on high protein diet I even have him on adrenal support supplement. I don’t know what else to do