Zimmy, my 11-year-old cockapoo, was diagnosed with Cushings a few months ago. He seemed to do ok on Vetoryl for two months but started losing his appetite and ability to go down stairs a few weeks ago. Yet, doc still wanted to raise his dose after seeing ACTH results. But didn't after I flagged concerns about his waning appetite.
Then, he stopped eating anything, vomited, had diarrhea, and was hospitalized for a few days. The med was stopped and he had a series of tests. High calcium score in his blood but ultrasound showed no significant irregularities. Waiting for results of parathyroid test which vet is guessing may be the problem since she argues that he was fine on Vetoryl for a few months.
Does anyone know if the bad effects of Vetoryl can be cumulative? Vet told me to start him on the drug again while we wait for parathyroid results...and the next day he vomited, had diarrhea, and stopped eating. The answer seems obvious that it's a bad reaction to the drug now although possibly the parathyroid is making it worse. I'm gradually getting him to eat a little as the drug leaves his system -- same as the first time he crashed.
Haven't decided how to resume Cushings care. Options are to try dividing up his current 30mg dose into the morning and afternoon to see if he'll tolerate it better. Or to simply see if he will tolerate a lower dose. Any advice?