Re: Cushings/Diabetes BUN & Creatinine Elevated
Good to hear from you again but sorry to hear Yukon has pancreatitis. I hope he is soon well and back on his feet. As for Cushing's causing Addison's, I've never heard nor read of any such thing...but I could be wrong; I don't claim to be an expert. If the dog were on treatment then an overdose of the med, Vetoryl/Trilostane or Lysodren/Mitotane, could cause an Addison's crisis (not permanent) or true Addison's (permanent) by driving the cortisol too low and damaging the adrenal glands. Lignans doesn't have that ability at all to my knowledge. There is always the possibility that the Cushing's was a misdiagnosis in the first place but I think you would have seen signs of low cortisol long before now if that were the case with Yukon.
What caused the vet to say such a thing? Did they do an ACTH or are you seeing signs of Addison's? Signs may include weakness, depression, lack of appetite, vomiting, diarrhea, and occasionally increased thirst (polydipsia) and increased urine production (polyuria). Clinical exams may find dehydration, weak pulses and sometimes a slow, irregular heart rate. Lab work might show an increase in CREA and BUN, low GLUC, changes in WBC, increased potassium, decreased aldosterone, and dilute urine. BUT pancreastitis can throw a great many lab results out of whack so with this condition in play I wouldn't trust any diagnostics tests for either Cushing's or Addison's right now. Once Yukon is over the pancreatitis then you can take a look if needed.
Please let us know how he is doing!
Hugs,
Leslie
"May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"
Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.