Hello
My name is Joanna, from Poland in Europe, i have a dog golden retriever called Moby (Mobi), in June he will be 10 years old, he was diagnosed with Cushing in October,but he hasn't got lost of typical symptoms - he has only very big apetite. Cortisol in his first urine test was 8,41 ug/dl, then we did The Low Dose Dexamathasone Suppression Test, the cortisol was 6,54 after 4hours 2,00, after 8hours 1,96 - the test confirm the Cushing ,in my vet opition this is pituitary Cushing so he told me that vetoryl may not be effective. I asked him if we could try with this Vetoryl. We started with small dose 60mg, after 3 weeks we did urine test the cortisol was 15,4; my vet decided to try with 120mg dose, after 3 weeks the cortisol was over 20ug/dl. I don't know why the cortisol has increased after Vetoryl. We did The low dose test again on Monday, tomorrow we will go to vet to see these blood test. Moby isn't on Vetoryl since 19 January. Moby has also increased liver levels, his alkaline phosphatase now is 610,6 U/l . I don't know what to do, is there any others drugs for Cushing - for pituitary Cushing? i read about drug called Anipryl - what do You think will it help? or maybe we have to continue with Vetoryl? Did You heard about situation that Vetoryl didnt't help or increased cortisol?
What about alkaline phosphatase is it very high?
Moby weight is about 40 kg - almost 90 pounds,
please help me
best regards
Joanna with Moby