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Thread: suspected Cushings

  1. #111

    Default Re: suspected Cushings

    My dose is 22mg twice a day for a dog that is approx. 48lbs. Is that too much to start with?? I was under the impression that this would be a low starting dose. Was your dog's 10mg starting dose once a day or twice?? I worry about the cortisol level dropping too fast if my total daily dose is too high.
    I am very comfortable with the explanation of the ACTH draws and will make my needs known when I make the appointment with the office in about 10 days. I will also make sure that the same vet will be there in case there are problems as she agreed that we would follow Dr. Peterson's guidelines - she may not have informed the front office gals yet.
    Jan W.

  2. #112
    Join Date
    Jun 2012
    Location
    Canada
    Posts
    16,150

    Default Re: suspected Cushings

    No 22mg twice a day is not too much. Optimally I guess if you follow the 1mg/1lb, you'd be at 24 twice a day, so hopefully you won't have any issues with going too low. I wouldn't expect you to have any issues with that, but every dog can potentially react differently to any drug.

    Addy will tell you what Zoe was started at.

    Sharlene and Molly Muffin
    Sharlene and the late great diva - Molly muffin (always missed and never forgotten)

  3. #113
    Join Date
    Apr 2010
    Posts
    7,965

    Default Re: suspected Cushings

    Dr Peterson thought Zoe should start at 15mgs. She has inflammatory bowel disease so we were trying to prevent it flaring when we dropped her cortisol. Her IMS was nervous so she dropped the starting dose down to 10mgs once per day. I was fine with the 15.

    She did flare though and had loose stools, it took me 3 weeks to get control again of her IBD. Every time we changed her dose, she flared then finally adjusted to the medication and lower cortisol.

    I dont think you have to worry about your starting dose. Keep in mind too, my Zoe had very few symptoms, mostly skin/coat issues originally. We waited a year to start treating her as I had to fix her IBS first.

    Every dog is different and you just dont know how they will respond so when in doubt withhold the dose.

    You will do just fine.
    love,
    addy, zoe and koko


    My little dog - a heartbeat at my feet. ~Edith Wharton

    Memory is the power to gather roses in the winter

  4. #114

    Default Re: suspected Cushings

    I guess I am reading more into this stuff than necessary which is my usual!!! I guess it sounds right. It doesn't help much when I'm out of my blood pressure medication. I still have the other one I can take until they come in. My mailbox was found open 2 days in a row so worry. It's coming from Canada and is kinda late.
    I will quit panicking and leave you guys alone for awhile --- Thanks -I read all this stuff then I forget where I saw it and try to find it and never quite understand the search then I get off reading something else and never do find what I'm looking for.
    - One person wrote that they were wondering about the daylight savings time adjustment with the dogs - and yes my dogs are out of sorts --- I always thought they could read the clock, but they are an hour early looking for meals. So much for reading the clock!!
    For fun yesterday - I took my dogs out and did some AKC obedience training which I have given up but they were so used to that kind of stimulus for years that they are totally bored. It was actually fun because Cinder thought she knew what I wanted and ran Chamois off trying to get to the treats first. I realized why we never worked with them together before. But it was fun - I had a good laugh. Cinder can be such a clown when she is trying so hard to do what I say and I think her mind isn't clear either so she gets confused.
    It was amazing how much they remember and how much they want to forget!!! Again Thanks Jan W.

  5. #115
    Join Date
    Sep 2012
    Posts
    6,400

    Default Re: suspected Cushings

    Jan:
    If it were me, my preference would be 30 mg to start off with. I am an advocate of starting low. It may cost a little more, but you are surely saving that in worry. I believe in being cautious with this drug, as I have seen my share of problems happen on here form people starting dogs too high. I truly believe it is the safest method to try and ensure you have no problems. I would rather be safe than sorry. The choice however is yours, that is my preference as it gives the dogs body time to adjust to the drug. Remember these dogs have never had this in their system before. For example when I was first put on thyroid medicine I thought the top of my head was going to explode from a really bad pressure headache. It would not go away and I could hardly function. I told the Dr. and of course she said it was impossible and was not coming from the drug. I left and went to another Dr. her immediately told me you have to start at a low dose on these meds to get used to them and that won't happen. Sure as God made green apples he put me on a lower dose and I steadily increased it and no problem. These are powerful drugs and I think all precautions should be taken in the beginning to ensure a smooth journey. Hope all goes well. Blessings
    Patti
    Tipper and Tipper's Mom


    "The greatness of a nation can be judged by the way its animals are treated."
    Mahatma Ghandi

  6. #116

    Default Re: suspected Cushings

    I spoke with the vet the other day about starting with one capsule per day for a couple of days and she was ok with it. So I will start with 1 and if no problems I will increase as I feel she is doing.
    I already gave Cinder the first pill about an hour ago and I keep looking at her and asking her if she notices any difference yet!!!??? She doesn't answer me but she is looking back at me like I'm nuts. As soon as the sun peaks out I'll take my girls for a walk and then my son (the priest) should be coming and she gets pretty excited when he comes. I'm not sure why because he always brings his "bratty" little kid (Westie) and Cinder and Chamois aren't sure they like the whirling, white tornado called Sophie. Actually his Sophie is pretty good too she's a terrier and they have different personalities than labradors. Sophie is used to being an only child and thinks she should be the Queen Bee over my two big Labradors. And she is. Fun to watch.
    I'll keep you posted - so far so good!!! Jan W.

  7. #117
    Join Date
    Mar 2009
    Location
    rural central ARK
    Posts
    14,549

    Default Re: suspected Cushings

    I am partial to the Terrier breeds and one thing you must keep in mind with all those breeds is this - Terriers were created to rule the world! Just ask any one of them and they will tell you that is the absolute truth.
    "May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"

    Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.

  8. #118

    Default Re: suspected Cushings

    I think you are right - Sophie does rule the world. She is jealous of my one yellow lab and does not like her being close to me so she will jump up and try to squeeze between us on the couch. My yellow lab is jealous of the white tornado and purposely will jump up and lay down next to me with her head on my legs so Sophie can't get to me as easily. Otherwise, she hardly ever wants to be next to me anymore. She prefers her own space usually. They are strange creatures.
    So far Cinder (the black lab) is doing good on the trilostane. She is still thirsty and still hungry. She always drinks up the white tornadoes water when she comes even though she has her own. She did this today as well.
    I realize this is extremely early in the regime, but I am watching her every move. Poor thing. Jan W.

  9. #119
    Join Date
    Apr 2010
    Posts
    7,965

    Default Re: suspected Cushings

    Good, watch closely, larger dogs can sometimes be more sensitive to the drug, not to scare you off or anything. Depending when you start the full dose you might want to re explore when you are going to do the first ACTH test.
    love,
    addy, zoe and koko


    My little dog - a heartbeat at my feet. ~Edith Wharton

    Memory is the power to gather roses in the winter

  10. #120
    Join Date
    Mar 2013
    Posts
    3,022

    Default Re: suspected Cushings

    Jan, Daisy was super sensitive to the Trilostane in the beginning. She also has flare ups of IBD. Her IMS doc prescribed 1/16th of Tylan powder sprinkled on her breakfast and dinner. We haven't had a problem since.

    Since Tylan powder is naturally derived, the specialist said that it can be used indefinitely.
    Valerie

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    Daisy Bella

    "My sunshine doesn't come from the skies, it comes from the love in my dog's eyes." - Author Unknown

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