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Thread: Possible Cushing's, 8.5 y/o male Boxer (Sweet Jordan has passed)

  1. #121
    Join Date
    Feb 2012
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    Scotland
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    110

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    I'm sorry Jenn it's not an area I have any experience in. However there are a couple of UK companies who specialise in animal health / nutrition. I've used their horse and dog products and met their reps at horse shows and they've always been well informed and helpful. The 2 companies are Global Herbs and Naf Supplements. They both have helpline numbers on their websites.

  2. #122
    Join Date
    Mar 2009
    Location
    rural central ARK
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    14,549

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Hi Jenn,

    What counts is the amount of SDG that Jordan gets. If he is getting the amount he needs via the ground seed, then there is nothing wrong with using it. My concern, from my own lack of experience with them, would be regulating the dose of SDG day to day. I have used crushed flax hulls but they were ready to measure with the SDG amounts provided per scoop given. The cost factor sent me back to the capsules.

    Do you know how much SDG he gets each dose with the seed?

    How is he doing? Did you start the Anipryl?

    Leslie...if you have a few minutes to share what you're currently using and why, that'd be great, as it seems Jordan and Squirt have some things in common. I finished reading all 45 pages of your thread this morning, so I know some stuff, but not necessarily why.
    Missed this, too!

    Currently, Squirt is on -

    *HMR lignans (spruce vs flax), 1- 40mg daily; 3mg Melatonin 2x a day; and Lysodren, 125mg 2x week - for Atypical Cushing's (melatonin also has the ability to lower cortisol slightly)

    *4 drops of Burdock root tincture daily - for liver and gall bladder function

    *2 drops of Astragalus tincture daily - for immune support

    *1 -100mg PS 100 (Phosphatidylserine 100) - for continued mental acuity and aid in lowering cortisol

    *100mg SAMe daily - for liver function primarily, tho is has many benefits

    *Salmon oil daily - for inflammation

    *1/4 tablet daily of GlycoFlex III - for arthritis

    * she eats a diet designed by a nutritional consultant that is low fat, moderately high protein, moderate carbs (fairly high fiber)

    Think this is all! Hope this helps.

    Hugs,
    Leslie and the gang
    "May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"

    Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.

  3. #123
    Join Date
    Mar 2012
    Location
    Heidelberg, Germany
    Posts
    101

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Thanks, Ladies!

    I just dropped off the Anipryl 'script and will pick it up at 1800 this evening, so we'll probably get him started on it tomorrow. I say probably only because he's had a really good day today, and if that trend continues I might want to wait a day or so until he starts having 'off' days again...figuring that will provide more contrast so that I can tell if the pills have any effect. It's funny, but the last time we took them to camp for a weekend, this same thing happened - they were both exhausted yesterday when we picked them up, but today he's perkier than I've seen him in awhile - even picked up his Frisbee when I got home from the vet earlier!

    As to the lignan/flax situation, I think I might order some pills, because right now my method is far from scientific. I just looked on the interwebs until I found something that told me how many lignans would be in a tablespoon of ground flax, and have been dosing him accordingly. I do think that the flax and melatonin are working, at least to some degree, because his appetite has improved (which is to say, decreased), but I think I'd better be more precise with what he's getting, so that I can give it the best possible chance of succeeding.

    Thanks for the supplement suggestions, too - that's very helpful. I think I'll start adding some things once he's been on the Anipryl for a few weeks and we have any idea whether it's going to work or not. I don't want to add anything else at the same time as the drug.

    Wish me luck! I'll keep you all posted, of course. Thanks again!

    Jenn

  4. #124
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    Mar 2012
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    Heidelberg, Germany
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    101

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Hey guys...can somebody give me some ideas here? Jordan is peeing brown, as of at least this morning, which is when I first noticed it. I was hopeful that it was from me sharing a red drink with him yesterday, but I can't imagine that's the problem seeing as that's been almost 24 hours ago. He doesn't seem sick, I took his temp and it's normal.

    We started the Anipryl on Tuesday, so the timing of this new problem is highly coincidental, to the point of suspect.

    Thoughts? Suggestions? I'm so, so exhausted with all of this. I'm on such an emotional roller coaster right now...he's had a fantastic week, more active and alert than in awhile...and now this.

    Help?

    Jenn

  5. #125
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    Apr 2009
    Location
    Nebraska
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    5,606

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Hi! Call your vet and gather some urine to take in. YOu have to rule out that it is blood. That is what I would do. You might also google anipryl and brown urine to see if anyone else commented online about it. Sorry for the short reply - am off to work. Kim

  6. #126
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    Mar 2009
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    rural central ARK
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    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Hi Jenn,

    Have you noticed a strong odor with the urine? Does he seem to strain to pee or does it take longer? Is his stream steady? I have a friend who gets kidney stones when she drinks things that have red dye in them, like Fruit Punch, and that was my first thought when you said you shared a drink with him. Squirt didn't have any urinary reactions to the Anipryl but that doesn't mean it isn't possible.

    Let us know what the vet says!
    Hugs,
    Leslie and the gang
    "May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"

    Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.

  7. #127
    Join Date
    Mar 2012
    Location
    Heidelberg, Germany
    Posts
    101

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Thanks, y'all. I'd already rung the vet, but he's in surgery until four, so I have to call back then. Meanwhile, I've spoken to my mum, who has me in a panic over kidney or liver failure, so I'm going to run (literally...oh great...add 'in the rain' to that now) up to the train station to retrieve our car, in case the vet says to bring him in immediately.

    He has a pretty steady stream, no straining, although now he's starting to be shy because I keep chasing him with the sample jar. It smells...but I honestly can't say I know what I'm looking for there...it smells like pee. I dumped out the sample I tookfrom earlier, in hopes of getting a cleaner one, and when I did, there was quite a bit of sediment in it, as there seems to be in the new sample I just gathered.

    So, as much as I'd like to think this is Crystal Light related, I'm having my doubts.

    Oh geez...it's a full-on gale storm out there. This day just keeps getting better. I'll probably get back from the train station just in time to call the vet at four, so stay tuned. Please!

    Hugs,
    Jenn

  8. #128
    Join Date
    Mar 2012
    Location
    Heidelberg, Germany
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    101

    Default Re: Possible Cushing's, need advice on next steps (Jordan) 8.5 y/o male Boxer

    Just got off the phone with the vet, and he is saying that the brown urine is a side effect of the Anipryl and not to worry about it?!?!

    Does that seem right? Anyone else with Anipryl have this experience? I already searched 'Anipryl/brown urine' and came up with nothing.

    I think I'm going to translate the product insert and see what I come up with. This just doesn't seem right....though I'd be thrilled if it is.

    Best,
    Jenn

  9. #129
    Join Date
    Mar 2012
    Location
    Heidelberg, Germany
    Posts
    101

    Default Can Anipryl causing urine discoloration?

    I'm sorry to start a new thread...I didn't know how else to bring this to the forefront.

    Can anyone tell me if their pup has experienced discolored urine - in our case, very dark brown - after taking Anipryl? We started on Tuesday, and I first noticed it this morning. I had to call the doc back three times before getting a response, through one of the receptionists, that "The medication can cause this" and not to worry if he is eating, drinking, and feeling fine.

    While I would love for this to be the answer, I cannot find anything in the product literature, which I had to translate from German. Additionally, I rang the company here who makes it (selegiline AL, from Aliud Pharma) and after much jumping through language barrier hoops, was told that they cannot say whether it would cause this problem in dogs, but it does not cause it in humans.

    Has anyone else had this experience? I've been through too much with this to trust the vet at his word, unfortunately.

    Again...sorry for the additional thread, and thanks for any help anybody can offer.
    Jenn

  10. #130
    Join Date
    Mar 2012
    Location
    Heidelberg, Germany
    Posts
    101

    Default Re: Can Anipryl causing urine discoloration?

    Oy. Can Anipryl CAUSE urine discoloration, not causING. As you can see, I'm a bit of a mess over this.

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