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Thread: 9 YO Cairn goes for LDDS test next week

  1. #101
    Join Date
    Apr 2010
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    7,965

    Default Re: 9 YO Cairn goes for LDDS test next week

    Kim knows her stuff so please read her posts and follow her advice.

    We are here for you.
    love,
    addy, zoe and koko


    My little dog - a heartbeat at my feet. ~Edith Wharton

    Memory is the power to gather roses in the winter

  2. #102
    Join Date
    Mar 2009
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    rural central ARK
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    14,549

    Default Re: 9 YO Cairn goes for LDDS test next week

    Hi Jodi,

    Don't wait for the vet to tell you to stop - stop now. No more Lyso and do not give the pred unless you see signs of a crisis. Leaving food in the bowl is not a crisis.

    If she has already had the morning dose today, watch her very carefully today and tomorrow. It is possible a dose this morning could have been too much so be that hovering Hawk!

    You want the ACTH to be as close to the 48 hour mark as possible after the last dose of Lyso so if she has had a dose this morning, Fri morning will be ok. If the last dose was yesterday, then Thurs would be better. Lyso peaks at 48 hours.

    Let us know how things are going and know we are all right here with you!
    Hugs,
    Leslie and the gang
    "May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"

    Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.

  3. #103

    Default Re: 9 YO Cairn goes for LDDS test next week

    Spoke to the vet.. no dose tonight.. I have spoken to mom.. she has the prednisone and knows what to do... ACTH test tomorrow morning...
    Misty & Jodi


    Hope is that thing with feathers that perches in the soul and sings the tune without the words and never stops... at all. ~Emily Dickinson

  4. #104

    Default Re: 9 YO Cairn goes for LDDS test next week

    1/2 (usual )dose given this morning.. NO Prednisone was given with any doses.. I picked it up at the vets to have on hand just in case... so far today.. she seems ok...
    Misty & Jodi


    Hope is that thing with feathers that perches in the soul and sings the tune without the words and never stops... at all. ~Emily Dickinson

  5. #105
    Join Date
    Mar 2009
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    rural central ARK
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    14,549

    Default Re: 9 YO Cairn goes for LDDS test next week

    Jodi,

    Tomorrow morning may be too soon. I would want to wait until at least Thurs afternoon, preferably Fri., since she had a dose this morning. The Lyso will continue building and working for 48 hours which means a reading tomorrow will not tell the true picture - it may show the cortisol higher than it actually would be given time which could lead the vet to conclude Misty isn't loaded when she really is. I may be off base here and if I am I hope someone will come along and let us know.

    Hugs,
    Leslie and the gang
    "May you know that absence is full of tender presence and that nothing is ever lost or forgotten." John O'Donahue, "Eternal Echoes"

    Death is not a changing of worlds as most imagine, as much as the walls of this world infinitely expanding.

  6. #106

    Default Re: 9 YO Cairn goes for LDDS test next week

    Original plans was for her to take medicine up until the night before the ACTH if she hadn't shown any signs of loading... .. So, your thoughts??
    Misty & Jodi


    Hope is that thing with feathers that perches in the soul and sings the tune without the words and never stops... at all. ~Emily Dickinson

  7. #107
    Join Date
    Apr 2009
    Location
    Nebraska
    Posts
    5,606

    Default Re: 9 YO Cairn goes for LDDS test next week

    It doesn't work like that. Your vet is scheduling your dog's load around his schedule on Friday.

    Your dog loaded a day or two ago when she/he quit eating the entire bowl of food. You called the vet which was the right thing to do. Your vet told you to come in on friday for the test. Wrong. Your vet should have schedule the test 48 hrs from the last dose (more or less). Your vet should not have had you keep giving the drug. Thus my comment about lack of experience with it.

    You can't take the pill back and since you gave one this a.m. Friday is two days out. Go to the appointment but do NOT give any more lysodren. None whatsoever no matter what the vet says. You just have to trust us. Kim

  8. #108
    Join Date
    Apr 2008
    Location
    Tennessee
    Posts
    6,593

    Default Re: 9 YO Cairn goes for LDDS test next week

    Hi Jodi,

    It's been a while since I've had a chance to catch up on your thread so I started at the begining and whew, Misty has been a complex case for both your vet and the specialist. Misty doesn't have elevated cortisol based on the UTK test results and the more recent LDDS. A recent abdominal ultrasound showed exactly the same state of the organs as the original abdominal ultrasound done well over a year ago......same liver nodules and still normal adrenal glands.

    Most dogs with cushing's, who have been symptomatic for as long as Misty, have enlarged adrenal glands. The glands basically become big fatty masses and it is at this point where dogs are most sensitive to lysodren. Dogs that do not have cushing's or have normal adrenal glands have a poor response to Lysodren. As a matter of fact, misdiagnosis is one of the three reasons for a dog's failure to respond. It could be that Misty is an anomaly, a dog with normal adrenal glands and normal cortisol who actually responds to Lysodren in only three days, but I'm a doubting Thomas. Do you know if your vet is shooting for the same goal as he would with a dog with elevated cortisol, being within a therapeutic range of 1 - 5 ug/dl?

    Glynda

  9. #109

    Default Re: 9 YO Cairn goes for LDDS test next week

    I believe that even after 2 LDDS stims which she was borderline at 8 hours on the most recent test, vet asked for another ultrasound. Ultrasound was basically the same as the first one. No noteable differences. Nodular hyperplasia should not make ALKP levels continue to rise as in Misty's case, Internist stated that she could live with those levels, but she is showing almost every sign except hair loss of cushings. I do believe that the vet is aiming for therapeutic range of cortisol. But i'm not the vet. No more lysodren will be given.

    I really hope that I've done the right thing giving her Lysodren, but I am not giving any more doses, her ACTH test is for tomorrow AM.
    Misty & Jodi


    Hope is that thing with feathers that perches in the soul and sings the tune without the words and never stops... at all. ~Emily Dickinson

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