Thinking of you and Squirt today. Praying that all goes well.
Kathy and Buddy:)
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Thinking of you and Squirt today. Praying that all goes well.
Kathy and Buddy:)
Crossing fingers for you and Squirt.
Holy crap! :eek: The Proin she has been taking for incontinence may be at the root of many of the things I have been observing in Squirt over the last several months including the seizure a few weeks ago! So THAT will be stopped for good now and she will either wear diapers or sleep in the bathtub since she no longer leaks but pees lakes in her sleep. geez.....
http://www.fda.gov/downloads/AnimalV.../UCM296349.pdf
http://www.livestrong.com/article/25...ects-of-proin/Quote:
Table 6: Adverse reactions in the 28-day placebo-controlled clinical study
Adverse Reactions
PROIN
-
treated (N=123) (first number)
Placebo (N=61) (second number)
Emesis 20.3% 8.2%
Hypertension (≥ 160 mm Hg) 19.5% 14.7%
Anorexia 16.3% 3.3%
Body weight loss (≥5%) 16.1% 6.8%
Proteinuria 13.0% 8.2%
Anxiety/aggression/behavior change 9.7% 3.2%
Diarrhea 7.3% 9.8%
Polydipsia 6.5% 9.8%
Lethargy 5.7% 1.6%
Musculoskeletal disorder .2% 1.6%
Insomnia/sleep disorder 2.5% 0.0%
100's of pet owners believe Proin either directly or indirectly lead to their dog's host of health issues including death.Quote:
Allergic Reaction
Dogs that are allergic to phenylpropanolamine or any of the components of Prion should not be treated with this medication. Improper use of Proin by hypersensitive dogs may induce a severe and potentially life-threatening allergic reaction. Symptoms of a hypersensitive reaction in dogs include weakness, seizures, pale gums, facial swelling and difficulty breathing. Dogs who exhibit any of these side effects after taking a dose of Prion should be transported to an emergency veterinarian clinic immediately.
Thank you, dear friend, for calling me and filling me in on this drug. I trusted when I shouldn't have.
Omg! That is horrifying! I hope that once the Proin in out of her system (any word on how long that takes?) that other things will clear up and be better to.
Are there any herbal remedies to help with incontinence?
I bet that your vet is unaware of this, so might want to fill him in too as other dogs could see the same reactions if he prescribing Proin to them too.
Hugs,
Sharlene and Molly Muffin
Hey Les, here are the top six adverse events reported to the FDA for Proin (Phenylpropanolamine).
VOMITING
DEPRESSION/LETHARGY
ANOREXIA
CONVULSION(S)
ATAXIA
PRESSURE HI, BLD
DEATH
I know there are many pet owners who are convinced that Proin took their dog's life or has caused the onset of seizures. These people are working hard to get the word out, as well as asking people to report any adverse effects to their vets and insist that they file an adverse event report with FDA. There is a growing movement to get this drug off the market. If you notice that Squirt improves off of Proin, I would suggest you talk to Dr. B about it and ask him to report Squirt's side effects.
Do we have any others on the forum using prion?
I am on my phone but will start searching once I get to my computer
Sharlene
I used it with my Haley for years without problems. I do recall reading some negative things but by then she had already used it forever. I know someone once mentioned a holistic alternative but I cannot for the life of me remember what it was/is. Kim
I did quite a bit of reading on Proin last nite and it is horrifying what pet owners are reporting. One lady had a baby that acted much like Squirt and 2 weeks after stopping the Proin, her baby had massive seizures and had to be put down. Death from intracranial and intestinal bleeding, respiratory distress, stroke from high BP, continuing seizure disorders, on and on.
Then my mind went to work :eek::rolleyes: I am now wondering if the Proin has caused those muscles to simply stop working. This thought is based on the fact that instead of leaking she started completely emptying her bladder in her sleep after the Proin was stopped recently. She has been back on it off and on for about a week now - no accident last nite so I know the drug is still working on her. I have thought about how to flush her system but am not sure what would help and what might make the situation worse.
I also thought about the elevated EOS recently and the caution about pups with allergies to phenylpropanolamine and other ingredients in the drug. Is she allergic to these components? Was the Proin the cause of this sudden change with the EOS?
There will be discussion with Doc about Proin very soon. ;)
AND worrying about a new product I just got in that is supposed to help with pain as well as seizures called L-PhenyPet which is l-Phenylalanine. That ingredient and the phenylpropanolamine sound a whole lot alike in my mind so I have to research this very well before giving it to her. There may be no connection between the two and I do trust the source that recommended it for her completely. But Worry Wort Mom is in full battle mode at the moment. ;)
Now to share another thought that came to mind in the wee hours of the morning - a memory actually. I was thinking about diapers for Squirt and wondering how well she's gonna accept that, how to keep them on at night if she keeps trying to get them off. And the memory came rushing back. When Gia was an infant, I left her with her dad for a short while for the first time. When I came back home, I found my precious baby encased in duct tape. Her dad couldn't figure out how to work the disposable diaper. He said he couldn't find any diaper pins so he did the only thing he could think of - he duct taped the diaper on her. And, MAN, was she duct taped! :p I do have duct tape and scissors so we should be ok with diapers! :D I'll be at PetCo this morning to obtain some diapers so the adventure will begin soon. ;)
Thank you all again and again and again.
Hugs,
Leslie and the gang
Leslie:
I support you about the diapers. I think that is a good solution. If that does not work, I have in the past used the belly bands for male puppies to train them, and so they could not pee on the floor. With some minor adaptation they would work for a female. They are closed with strong velcro and they cannot remove them. They sell them on ebay, and if you wrote to one of the ladises that make them with measurements I am sure they can help. They are washable in the washer, so if they get wet no worry.
I am constantly amazed by all the wonderful moms on here who always have to find solutions to new problems. We are a very resilient group with a lot of ingenuity. Squirt ended up in the best home possible, as her mommy is her true hero. God bless you both as you both get back up when you are knocked down and keep fighting.
Patti
Hi Leslie,
From what you have researched do you think the problems with Proin have happened to dogs that are allergic to it or could it affect dogs that have been on it for years? Brin has been on the UK version, Propalin, for years with no problems that I have noticed. He suffers from ataxia which I am sure is neurological but he will be 17 this year so this is probably to be expected. I now worry whether I should take him off it or will this do more harm than good? I realise there can be reactions to most drugs but now I have it in my mind I can't help worrying about it!
Linda