Love the new avatar. That is such a cute picture.
Hope things are going better today.
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Love the new avatar. That is such a cute picture.
Hope things are going better today.
FYI, Maltese are also prone to higher ALKP and Fraser is a Maltese/Scotty mix. I think Fraser's breeding has a negligible impact on the severe ALKP elevation recently posted by Naomi.Quote:
Originally Posted by addy
Here in Canada my vet gave me Heppato Support supplements for molly's liver. It's what they use instead of Denamarin, which my vet had never heard of, so I guess that particular one isn't available for us here in Ca.
The new avatar pic is very cute.
Sharlene and Molly Muffin
What can I say? He never does things without doing then properly :oQuote:
Originally Posted by lulusmom
Anyway, Denamarin isnt available, but Denosyl seems to be the comparative choice. At $80 for 30 tabs though :eek:, I'm going to keep looking further for now. (even his Trilo is only $99 for 100) Will check into Heppato support and straight up Milk thistle, which is significantly cheaper.
Thanks for the help guys, really appreciated! :D
I'm still researching liver support things, how on earth does one find out an appropriate dose for Milk Thistle though? Every brand is a different strength, some have different qualities, and as they are all human grade, how on earth do you work out an appropriate dose for a 9.9kg Scotty mix dog?
But other than that, now I have another question. This requires a little background story though.
My Sister has a 2 year old Aussie Shepherd, Mika, who stayed with us for 10 days about 2-3 weeks ago. This happened to coincide with a time that Fraser really got his pep back and was looking pretty spunky. So when we would all go for a run at the park, Mika being a working dog runs for a solid hour after the ball - but apparently when she gets hot she must put off some kind of a scent that Fraser finds particularly appealing and he goes all frisky! Not kidding, he's like a horny old man! Constantly tries to bury his nose in her back (not her backside thank God - he is partial to giving people French Kisses), his ears go back and high, tail wagging, like he's just found a bitch in heat! :eek: They are both sterilised so what gives?
Last week when he got the flu, he was really down for a few days, but now that he's over it and we are back in circulation again, we went for a walk with Mika again today. He did it again! Which just proves it is not a one off, it's now happened over a dozen times. All his life, he will take an instant liking to a dog every now and then and stick his nose where it really doesn't belong, to the point of following them an entire oval length on occasion, but this is just another level. I am wondering, is this trilostane related, or does Mika just really smell that beautiful to him? No other dog does it to her (there were 7 in the pack today) just my horny little toad. :p (Keep in mind, he is 13 and was sterilised 12 years ago!)
What gives? 2 questions for you today. :D:D
Sounds like Frasier has himself a girlfriend and he really likes the way she smells. ;) It might just a be a smell that he really likes and wants to be around. Some dogs are more smell oriented than sight oriented and (I know Llahso's are smell oriented over sight), not sure about Frasiers mix though.
I have never read anything about Trilostane having that side effect though. So, new one. I can't wait to see what the others think of. :)
Sharlene and Molly Muffin
Quote:
Originally Posted by SoggyDoggy
http://www.littlebigcat.com/health/m...a-wonder-herb/Quote:
Dosage and administration
The standard dosage of milk thistle seed extract is based on a silymarin content of around 80 percent; most supplements contain anywhere from 50-500 milligrams (175 mg is typical). Silymarin is found mostly in milk thistle seeds, but in low amounts. Therefore a milk thistle seed extract will contain the richest source of this active component, as well as other natural compounds found in the seeds.
Because of its excellent safety record and lack of adverse drug interactions, when I’m treating a very sick animal with advanced liver disease, I do not hesitate to use the full human dose–up to 200 mg per 10 pounds of body weight–of milk thistle extract daily. For most purposes, however, one-third to one-half of that dose is more than adequate. (Animals with liver disease typically will not eat, but it’s a simple matter to open up a capsule, mix the appropriate amount of powdered herb with a little blenderized food or baby food, and feed by syringe.) Too high a dose can cause an upset tummy, gas, or mild diarrhea; these are easily resolved by giving less.
Human research studies have shown that it is more effective to administer this herb in three or four small portions over the day than in one large daily dose. When it is not possible to split the daily dose and administer the fractional portions three or four times a day, give it at least twice a day.
The capsule form is easy to find – any health food store, and even most pharmacies and grocers, will have them in stock. The herb also comes in a liquid extract, but most human products contain a fair bit of alcohol. If you prefer a liquid preparation, get one specifically intended for use in animals.
NOTE: Consumer Lab® released a report in December 2009 regarding test results from 10 commercial milk thistle preparations. Only Jarrow Formulas® Milk Thistle contained the industry standard 70% silymarin; all the rest fell short. They suggest using a product containing milk thistle “seed extract” as opposed to “seed powder” or “whole herb” to get the most silymarin.
So, my calculation for Fraser's weight of about 22 lbs would be 200mg split and given 3-4 times a day.
I am giving Squirt Milk Thistle Seed powder from Mountain Rose Herbs - it is a bulk dry herb. She has had trouble taking the capsules and the alcohol based tincture of milk thistle so I am trying the dry herb. She weighs a little over 13lbs. and gets 1/8 tsp/day of the powder at the moment with the intent to increase to 1/4 tsp/day if she can tolerate it. So far, so good! The powder is $3.75 for 4 ozs from MRH so it will last a while! ;)
Just saw your question on the amount of milk thistle it's OK to give - in case it helps I used to give Hamish one Hepato Support pill (which I believe contained 90mg of milk thistle) plus one S-Adenosyl 100 (which I believe contained 10mg of milk thistle). This combination seemed to help to lower his ALT (from the 380 range to the 200 range in 4 months) but had no impact on his ALKP.
One vet thought the SAMe shouldn't be a long term medication whilst the other thought it was!! Also if you do give a SAMe you should try to give it at least 2 hours after food / 1 hour before (despite the vet tech telling me to give with food!).
I bought the Hepato Support it in Canada, however it would have been around $60 for 90 pills if I had bought it in the US, and the S-Adenosyl 100 used to be around $40 for 60 pills when I bought it in the US.
I asked the vet to check the max. milk thistle dose and she said that 100mg was OK for his weight (approx. 14lbs / 7.5kgs). I wouldn't give any of the above without checking the dosage etc. with a vet.
p.s. love the new pic of Fraser
Quote:
FYI, Maltese are also prone to higher ALKP and Fraser is a Maltese/Scotty mix. I think Fraser's breeding has a negligible impact on the severe ALKP elevation recently posted by Naomi.
Well, gosh, Naomi, I sure hope you did not read that into my post to you. That sure was never my intention, to say Fraser's high liver values were because he was a Scotty. It was more of an aside comment meaning they can be prone to them.:o:o:o:o