My girl pug (confirmed Cushings & confirmed calcinosis cutis) / Tobey has passed

I think the downside is concerns that it is not as effective, especially if the pharmacy used is not compounding correctly. I believe a study was conducted that showed many compounded medications were not as effective.

Of course, a lot of people use the compounded trilostane with success. It seems there are a few trusted pharmacies (diamondback and wedgewood are the only two I see on here a lot).

My vet is personally not a fan of compounding either, unless absolutely necessary. If cost ever became a big factor for me, since Tobey goes through a box of 10mg per week, then I would need to look into compounded. But, for now, I am sticking with what is working!

Good to know. I have a local pharm where I get it from and it is actually more expensive than getting through Valley Vet but I hate shoving so many pills down Jed's throat and it alleviated the risk of me giving him the wrong amount.

Jed goes for next ACTH tomorrow so I will see what that shows but he has not been great for the last 2 weeks..appetite is not there but he also hurt his foot/toe so I was thinking it was more because he was in pain.

I will prob just go back to the vetoryl. I will tell you the two days after I gave him the wrong dose and we stopped his meds he was acting like old Jed. Lots of energy and eating great. These meds are really affecting him. I wish I could stop them but then I worry about his CC getting worse.

The price of cortrosyn has come down!

I'll be buying a 1ml bottle next week. It's $322.67 for the entire bottle. I'll get 4-5 doses out of that. :) I feel like it was much more expensive last time I purchased a bottle.

MERRY CHRISTMAS RENEE!!! Of anyone maybe you will have the white Christmas up in Alaska??! Hope you and Tobey and the gang have a lovely time xxxxxxx

Merry Christmas Renee and Tobey!!

Hope you are having wonderful holidays

hugs

I hope everyone had a wonderful Christmas! We had a very nice day, quiet and stayed home.

That said - 2 not so good things happened. Tobey had an isolated grand mal seizure on Christmas Eve. She recovered fine and is acting perfectly normal.

Then, her medicine (vetoryl) must have arrived after I checked the mail on Wednesday, because I just pulled the box out of the mailbox last night. That means her vetoryl was outside in 20-ish degree weather for 24 hours. Ugh. I tried calling Dechra, but they are closed until next monday. The box clearly says temperature sensitive on it too! I'll be contacting the post office, but I don't have high hopes they will care at all.

Hi Renee

Wonder what that seizure was all about, not related to her being unwell recently? Hopefully just a one-off that we see occasionally.

Frozen Vetoryl, hard to trust it after that happens if it is so temperature sensitive, do you have enough of old stock to last till you can contact Dechra to see if it is OK to use it? x

Crud I do hope that was a one off with the seizure. Don't want to get those going. She's never had one before?
Fooey on the meds in the cold. Hope it wouldn't hurt them as is the cold and not the heat. Cross fingers for that one

We had a quiet holiday at home too for Christmas Day, must say was nice after the hussle and bussle of the season.

hugs

I'm glad you had a nice Christmas. It was so chaotic at my house I was ready to take the pups and go sit in the car. LOL. I hate that about the seizure tho. I hope everything is still ok now and you don't get any repeat performances. The meds... I never realized that there could be an issue with the temps. That's good information for us all to know. It will be interesting to see what Dechra says.

Hugs to you and Tobey. :)

Well, I caught my postman yesterday and asked him about the medication. Since it's marked temperature sensitive, fragile, and urgent - I asked why he didn't bring it to the door. Of course he said that since it's so busy from the holidays, they don't really look at the packaging or read anything other than delivery address. If the warnings on the box had been in bright red or something else (just black lettering is on the package) he may have noticed it. I can try making a claim at the post office, but I have to prove damage. He also said it's likely the medicine is outdoors at the airport while it's being transported anyway.... so, it was probably subjected to cold temps before it even made it to my mailbox.

UGH.

Then, to top this all off, Tobey broke off a tooth last night. :( I'm guessing a dental is going to be needed.

Bah humbug!