Davis tested her for everything, we do not live in an area that has issues with lyme disease, we are in the san francisco bay area.
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Davis tested her for everything, we do not live in an area that has issues with lyme disease, we are in the san francisco bay area.
Yes it is 10 mg capsules and yes it is brand name, Davis added the label to wear gloves. Since I can not get pregnant does it really matter or not whether if I wear gloves?
Dawn
Ok, it was an idea.
Now that I think of it, I know two people who had Bell's and in both people, it resolved and you wouldn't know today.
Can you email Davis and ask them about the basis for their warning since it is not a warning that the manufacturer includes nor is commonly recommended by other centers or pharmacies. Maybe they think they know something that others do not. :eek:Quote:
Originally Posted by Dawn Anderson
Marianne
Marianne, the warnings may come from the Safety Data Sheet for Trilostane. A quick bit of research revealed that the GHS (Global Harmonized System) is a system of classifications and labeling of chemicals. The Safety Data Sheet does list Precaution Codes P264: Wash {hands} thoroughly after handling and P280: Wear {protective gloves/protective clothing/eye protection/face protection}. They also list P362+364: Take off contaminated clothing and wash it before reuse. I don't think UC Davis instructs their clients to do this. I do know that Safety Data Sheets are routinely used by OSHA and suspect since this is for 100% concentration of the chemical, these precautions would definitely apply to anyone in working in manufacture, processing or packaging of the chemical, but not so much pet owners who are administering a finished drug.
I have an audio of Dr. Feldman that predates Vetoryl and he said that he instructs his clients to not open the capsules to split the dose but he knows that some of them do because they can't afford to waste what they have when they need to do a dosing adjustment. It could be that those warnings insure that anyone foolish enough to open a capsule will wear gloves and wash their hands.
Drs. Foster and Smith also has a similar warning on their Trilostane Page.
https://www.caymanchem.com/msdss/14164m.pdf
Yes, I agree with you that the Safety Data Sheets relate to production workers as opposed to pet owners. Probably the SDS for virtually any drug carries a warning, though, re: the use of gloves among workers who are handling it and that doesn't typically translate to warnings for consumers. It has not been the norm in the past for owners to be instructed to wear gloves with trilostane, so I'm wondering if Davis has determined that there is some new sensitivity to be concerned about. If not, it seems to me as though they're likely to scare the crap out of people unnecessarily and maybe make some owners shy away from even giving the drug. :o
Marianne
Marianne, I was thinking that too. Something as scary as being instructed to wear gloves when handling makes it sound much less safe than it is. Not that there aren't risks, but it seems a bit overkill.
It's possible that UC Davis is just taking precautions in case their clients may be pregnant or trying to conceive. Vetoryl's safety sheet filed with the FDA states that Trilostane has caused early pregnancy loss in laboratory animals. I do know that the lab animals they are referring to were monkeys. It is much more common for a vet to tell a pet owner to wear gloves when handling Lysodren for the same reason. I did find the Dechra pet owner handout on Dermcare's site. I couldn't figure out who Dermcare was until I found their name on one of Dechra's financial statements as being the company that launched Vetoryl when it was approved in Australia. Anyway, the handout says wash hands and do not handle if pregnant or trying to conceive.
http://www.dermcare.com.au/images/ve...yl_handout.pdf
Read everything to daddy and he still want me to wear the gloves, he is certified in safety data ( he is the shop foreman at the dealership) and said that there is a reason for the label and gloves that were sent with the rx and that I am to follow the instruction, he will bring home a couple of boxes of gloves from work so that I don't have to keep reusing the set that I got with the rx. Like he says safety first.
So I will wear the gloves which I think is over kill since I CAN NOT get pregnant, to keep him happy and peace in our house.
Dawn and Miss Buttercup
He worries about you And Buttercup. I can't fault the man for that :) My husband would be the same. Is the same. :)
I don't know if it is just due to pregnancy concerns or if there is something new, and I can certainly see where Davis would want to take all precautions since they tend to know the canine patients but not necessarily the health of the humans involved.
hugs,
Sharlene and Molly Muffin