Molly, 13 yr, shih tzu - lhasa aspo - Molly has passed

Thanks Judi. I read that one and a couple others. Enalapril is the choice drug in the USA while benazepril is the choice drug in Canada. There is no difference really in how they will affect the UPC. Those are the top 2 choices.

Now dang if I didn't find another article about Losartan raising potassium in when used in conjuncture with an ACE inhibitor like banazepril. Well, that's not good, as on her renal profile last week, this is her potassium level currently:

6.0 mmol range 3.6 - 6.0 mmol dang it.
Because there is a risk of the banazepril raising the potassium too. In fact she is right at the highest end already, so how can I add something that will maybe help with the protein loss but raise her into dangerous levels of potassium.
This just seems impossible sometimes, the more I read!

I just don't really know what to do at this point.

We'll try to get the cortisol down lower and hope that helps I guess. Then I'll have to talk to the IMS about that potassium issue too.

If you find anything, holler. I'm game to read anything at this point. Though I admit my head hurts from all of it. LOL

I looked at some more articles about losartan and several of them referred to losartan as "losartan potassium"!

That doesn't sound very promising does it. Grrrr.

Thanks. I'm going to look up that phrase tomorrow.

Hey Sharlene,

When I get home I will search and see what I can find, I thought :confused::eek: that one of the difference between the two is how they are metabolized/excreted, one is by the liver and the other through the kidneys.

From what I read Lori I think that is one of the differences.

I'll have to see f I can find the article that talked about it. I know the first was human patients given both had increased potassium. The other article talked about two different arb that ended up increasing potassium in dogs.

This is interesting. Last slide a bit scary

http://www.canwestconference.ca/PDF/...ria_Slides.pdf

Great find! According to that the side effects of ARB and ACEi are the same. It's good to know that if the ACEi does not reduce the Proteinuria than Losartan can be used along with the ACEi.

The issue is going to be the potassium. If it causes potassium to raise I don't think we will be able to use it.

Hi Sharlene,
I am not sure if this is helpful but my boys are both on enalapril and their kidney values became elevated, not terribly elevated but over the normal range.

We had their US yesterday for their tumors and heart disease and blood work to check their kidneys etc and will have the results later today and will let you know if their potassium and kidney values if this will help you.

Thanks Vicki! I appreciate that!