Skippy has passed; 12 y/o Yorkie with likely pituitary tumor (Trilostane)

I'm following along too, and sending huge loving bugs.

Dehydration can cause a high BIN level and can even increase the creatinine temporarily. Getting fluids in by an IV or sub q would help with dehydration.

With kidney disease the phosphorus level will climb and when it gets elevated it does cause nausea. Did the IMS mention any increase with his phosphorus?

Hmm, yes if he is dehydrated then that could affect his kidney values (BUN and Creatinine) as Lori mentioned.

5ug is a good place to be cortisol wise if on vetroyl.

I've always been iffy as to whether to continue vetroyl if kidney problems arise, since dechra has said not to give to dogs with renal disease.

You don't want dehydration for sure. Would it make a difference if he were to get an iv for fluids do they think? Then take him off the vetroyl and recheck numbers in a week?

Thanks you guys. No mention of phosphorus level. I really wonder about the issue of dehydration; he continues to drink A LOT. Also, I give him beef broth in his food as he sure doesn't like dry kibble. I haven't measured water lately but I will. And, now that he's off Vetoryl I would expect him to drink even more. Also, while stool was firm this morning and I did't dose him with Metronidazole, soft stool has returned. No mention by IMS of further hydrating him. He is eating today but still very lethargic.

The "5" was basil cortisol. (Normal range is 1 -6.) On 10/9 it was 3. I am uncertain as to whether basil cortisol means anything with a Cush pup. My error was to not request a stim on 10/9 after he had been on 10 mg BID for three weeks. He tolerated that well but still had clinical symptoms of Cushing's OR maybe it was the kidney problem and not the Vetoryl increase to 15mg. But the dose increase was based on what they were "comfortable" with based on clinical signs and I agreed. We are where we are. If I see further signs of dehydration before next week, I'll call them immediately. Since he's off Vetoryl, I could try offering the Royal Canin Select and if he won't eat it. let him go without food until he gets hungrier. I just don't know. As he get's sicker, I get" stupider".

I know that feeling. Well normally the post is higher than the base. So he isn't being overdosed. That means the 15mg is likely okay. And if drinking that much probably not dehydrated either.
It is all so dang complicated to try and figure out. Grrrr

Yes, but I so appreciate your and everyone's support. Six outs so far tonight; but he is drinking steadily and ate including Royal Canin so I hope he's stable for the moment. Must sleep so I can do the 4 am shift!
Thanks heaps!

Hoping that skippy is doing okay. Is he still eating? How is the water levels doing?

Skippy is eating, drinking, peeing, and no diarrhea at the moment. He is much less lethargic, but no ball of fire. He does want to get up on sofa, bed, etc. and puts his paws up but won't try to jump. He shows no signs of renal failure but I have no idea of how he is doing overall. He will be tested Tuesday early AM; I'll post after I know more. Thanks for your support!

Well this sounds encouraging. Skippy is blessed to have you in his corner.

Kathy

This is super positive! Great he is eating, no diarrhea, and sounds much more energetic than he was.

Molly completely quit jumping up eventually and would put her paws up and wait for her "lift" I'd say, you need a lift up molly and she'd just look and wag her tail. If you ignored her she would eventually bark at you and put her paws back up. Which I always found just hilarious, but then it was all part of Diva molly and how she ran our lives.

Skippy is letting you know in his own adorable way, exactly what he wants you to do.

Oh my Carole, what a journey you & Skippy have been on! I'm so happy that your sweet, strong boy is doing better-you are both amazing! what may seem like small victories mean so much, don't they...
all the best to to you both