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Dear Addy
Thanks for the concern.
Will try to post more tomorrow. I am not doing the rabies shot. My vet who does the acupuncture says with the cushing , Apollo has enough going on, so doesn't want me to do. I know of some dogs who had horrible reactions to the shot. I know a few people who should get a rabies shot.:D:eek::p
I just starting crying out of the blue about everything today, like a running faucet. Sometimes we just need to let it all out.
Take care my friend , How is Zoe doing.
Hi Sonja,
I'm waiting a bit on the rabies shot too per my conversation with Dr. Schultz. Would like to wait a few more months, closer to the 4 year mark if possible. She is not snappy anymore when you pick her up. I keep giving her chicken before, during and after we pick her up, she is happier again about it and stopped trying to bite. Also, I think it does not hurt her now to be picked up since her tummy is better.
QUESTION:I have to be careful with the lignans with Zoe, her system is so sensitive. I have to split the dose up, she gets one capsule in the late morning in a snack and 1 capsule in the evening with a snack. This has worked well for her and her system is tolerating the lignans. I want to add another 1/2 capsule but when I added it to the evening dose, it bothered her tummy. You could tell the way she laid on the floor. Could I give the 1/2 capsule with her evening meal, 2 hours before the night time capsule? Does it matter she does not get the lignans in one dose? I did that last night and she was much better.
Also do I have the dose right? She is 18 pounds so needs 18 mgs lignan. Vitacost is 40mg capsule with 20% lignans so I figure 8 mgs of lignans per capsule. 2.5 would be 20 mgs but I would rather be over than continue under if she can tolerate it.
Suggestions? Thoughts? Thank you for your help and experience:)
She has again adjusted to the extra 1 mg of melatonin and was perky last night when I got home from work. Can't believe how slow I have to go with all of this so we don't tip the scales out of favor:eek:
ONE MORE THING- I just reread in our Resource section about the intermediate and sex hormones. I did not know that a NAI could cause elevation in those as well:eek: Does it make sense that Zoe's Estradiol was elevated before she was stimmed then went DOWN after? What is that about? She was elevated 4 out of 5 intermediates BEFORE she was stimmed. I keep trying to research that.
LAST THING- I want to thank ALL of you who have posted on my thread. I appreciate your experience, knowledge and support so very much:) I feel I learn something everyday and Leslie and Glynda and John, thank you for making me laugh when I need it so badly:D:D:D
Love to all of you,
Addy
With Harley having such high elevations in his estradiol I did give him more than the required recommended dose and I did split it up...some in the morning and some in the evening.Quote:
Originally Posted by addy
By my calculations you are correct! ;):DQuote:
Originally Posted by addy
I don't if this will help you or not, this is email I received from Dr Oliver about estradiol:Quote:
Originally Posted by addy
You're doing a wonderful job, Addy!Quote:
Estradiol is definitely not affected by ACTH or Dexamethasone, so you almost always see similar baseline and stim results in our canine adrenal panel. In fact, the baseline tends to be higher than the stim values in most cases. In Harley’s case, they are virtually identical. The estradiol can definitely be secreted by adrenal tissues and primary adrenal tumors, but also is formed in other places, like fat cells, hair follicles and the liver. If other hormones are increased on our panel, then it’s likely that the estradiol is being secreted by the adrenals.
Love and hugs,
Lori
Thank you Lori!:)
If the estradiol was formed in the hair follicles could that be why her coat and tail are bad?Quote:
The estradiol can definitely be secreted by adrenal tissues and primary adrenal tumors, but also is formed in other places, like fat cells, hair follicles and the liver.
Does that point to adrenal tumor? IMS said thought Zoe had PDH though one adrenal gland was slightlyQuote:
If other hormones are increased on our panel, then it’s likely that the estradiol is being secreted by the adrenals.
larger than the other, she did not think adrenal but I did not do low dose dex test because of Zoe's stress levels, so would that mean we don't really know for sure what kind she has?
Lori- I am thinking of adding maintenance dose of lysodren when I have to. My thoughts are: she is soooooo touchy and I never know how she is going to react and she will get diarrhea at the drop of a hat. My thought was if I did maintenance dose first, I could see how she adjusts to it. If I did maintenance dose first does that have any negative impact if I would have to change to loading? Just thinking ahead, trying to plan the end of the reprieve.
Thank you:)
Hugs,
Addy
Hi Addy,Quote:
Originally Posted by addy
I don't see a bit of downside going the route of maint only Lysodren in a pup with symtoms and diagnostics supporting a Lysodren treatment. If the cortisol is near normal I really don't see another way to approach it. If a Dr. decides later that a loading is required I can imagine you would have two approaches, either suspend treatment for up to a month or resumption of significant symptoms or just be acutely aware that the Lysodren already circulating in the pup's system will likely result in a very short loading.
Scott
Wish I could help.
Apollo is falling a lot, will hold off on rabies shot, may not do at all.
But can't give input on this.
You and Zoe are in my prayers.
something is wrong. I upped the last 1mg of melatonin 2weeks ago today. She was very spacey the first day and I changed our routine that day and she had a potty accident in the house. I attributed it to being spaced out on the melatonin. She seemed to adjust to it now and was perky when I got home from work the last two nights. Tuesday night I took pups for ride in the car, she jumped from back seat to front seat and then later when koko tried to join her on the car seat she held up back foot. Last night and this morning she could not jump on the bed but walks fine. Back leg seems stiff and would not let me stretch it out. We did not walk this morning, give leg a rest, now since she is up and moving I can stretch it out. But she came to me while I was getting ready and I did not think much of it, she had been out to do her business an hour before. She came to me again so I stopped and took her outside and she peed. But then in the house I found a pee accident. I don't think it was Koko, judging from her behavior it was Zoe. Also last night she wanted to sleep with me. She only does that when she does not feel good or a bad storm is coming. We had no storm.
1-Cushings getting worse
2-UTI
3-Diabetes
4-some kind of stone
She has been licking her potty off and on for the last year but we never find a UTI, she stopped for awhile the last 2 months and only did it occasionally, she is licking it more now.
This has just been since we upped the melatonin to 3mgs 2 times a day. Both accidents were in the AM not long after I gave her the melatonin.
Not sure what to make of this. Thoughts?
Addy
Hi Addy,
When Crys developed struvite crystals, she would lick her privates a LOT! She never developed stones and we treated her with anti-biotics and diet. The vet explained that the crystals irritate the urethra as they pass plus some will stay in the tubes, etc. causing more irritation, so they lick to sooth the area and try to remove the "pricklies".
I don't recall reading anything about melatonin having any affect on the crystals, but I was only concentrating on struvite and there are other kinds, each caused by different things.
When a pup is constantly licking, that usually indicates some problem somewhere and I would think your vet would have looked for crystals in the tests for UTIs, but one never knows.
Just my 2 cents worth as usual! :)
Hugs,
Leslie and the girls :D - always
Hi Addy,
Good input from Leslie, I just wanted to add that Roxee was checked numerous times for a UTI but came up negative. I was sure that something was wrong and insisted on a culture. Culture came up positive and she was put on antibiotics and cured.
I insisted because she was licking and because of the discoloration and some clumping of stuff around her private parts. We called it her twinkie :p Most dogs I have groomed that have a brownish discoloration seem to have some kind of infection and many times it is a yeast type infection.
Oh John and Leslie, thank you for the good input.:) Leslie, your 2 cents=1,000,000 cents:) Then I can call IMS and ask to bring her in for a culture?
I think I forgot to breathe this morning when I posted. I have been so scared she will develop diabetes and then with the leg thing AND the accident today I panicked:eek:
How do they find stones and crystals, through a culture too? I kept telling the vets she never used to lick herself before but they poopooed me:mad: They said well, maybe that is just the way she is. IMS did urine test and said it was clear and did not think much of the twinkie (thanks John, I like that)licking either.:confused:
I think I should insist now. For awhile I thought it was the wet grass in the morning bothering her twinkie but with 2 accidents in 2 weeks, something is wrong.
Thank you so very much for your input!!!!
Addy