Tipper - adrenal tumor/breathing issues

I have not yet found anything from Dr. P about twice day dosing being the better alternative for adrenal tumors though we know that it may be hard to control their cortisol so that could lead to twice day dosing. Zoe has always struggled with her evening dose.

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Pros and cons of Lysodren vs Vetoryl
So which drug to use—mitotane or trilostane? If the dog has PDH, she should respond clinically to either drug (1,4-6), but if an expanding pituitary tumor is present, that might lead to neurological signs within a few months (3,7). If the dog has an adrenal tumor, the standard doses of mitotane would be unlikely to help, but this failure to control the cortisol levels would help "suggest" that an adrenal tumor is the underlying cause (1,8,9).

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Use of standard doses of trilostane, on the other hand, is more effective in lowering cortisol values in dogs with adrenal tumors so this may be the way to go if the client refuses any additional workup (6,10). However, if adrenal carcinoma is present, this drug would do nothing to stop tumor invasion or metastasis. And again, if the dog has non-suppressible PDH with a pituitary macrotumor, this might lead to neurological signs within a few months.

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have a patient with an adrenal tumor. If I give VetorylR prior to surgery, will the mass
get smaller?
No. VetorylR has not cytotoxic effects on adrenal tumors. It will not shrink the mass or prevent metastatic spread. However, VetorylR does effectively control the clinical signs of HAC in these patients, and is licensed for use in dogs with adrenal tumors. Surgery is the optimal approach in these cases, but Vetoryl should be considered if the mass is inoperable or if other factors make surgery a poor choice

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Hi Patti.... isn't Tipper just the real smart one. I'll have to remember what she does in case when I get older I get tremors. It's actually quite cute to imagine.

It's dull and dreary here, and we are expecting snow this weekend as well, think it's coming here from your area.

Have a great weekend and glad to hear Lucky is feeling a bit better.

Have a great weekend.

Hugs from me and "mah boy"

Wow! That is so cool that Tipper is finding a way to handle the tremors. She is so smart!
I hope that Lucky gets better!

Hi Everyone:
It was literally a hair raising morning. I took Tipper out and put her behind the gate in the living room as I always do. The only problem when I went to walk away I heard hissing and screeching, here Lucky the cat that is sick decided for some reason to go into Tipper's space. He never does this as he knows Tipper does not like him. She was on him before I could blink, I quickly opened that gate and got her off him. He was so petrified at her he could not even think to jump the gate and get away. She had a mouthful of his hair and there were balls of it all over the floor. Poor Lucky and he is already sick on top of this. I checked Tipper's face and eyes then ran and got Lucky and checked him all over. She is still so powerful, you don't mess with Tipper. I know Lucky will never do that again ever. I am thankful neither one is hurt. Tipper slept well and walked already it is very cold but above 32 so she can go slowly. I am in the middle of filling out paper work for the nutritionist to help Tipper. It was so long and so detailed I thought I was going to have to name my kindergarten teacher. My God it took me 3 hours to complete, but I am thankful she is so thorough. I need to get this pound off Tipper and get her onto a healthy diet that benefits her body to help fight off this disease. I am wanting her to not be begging for food anymore as it breaks my heart to see her like this. I have asked the nutritionist to give me a recipe utilizing the chicken I already have for her as it was so costly. My vet is gone for about 10 days so I cannot have Lucky seen until he comes back for blood work, unless it is an emergency. Lucky seemed much better and eating on his own until the incident with Tipper. I keep checking on him periodically. These critters are going to give me heart attack yet. At 3 o'clock in the morning the ice maker was making a terrible noise. It was clogged up and could not drop the ice. I had to get up and empty the_____ thing and have been up ever since. I hope I sleep tonite as Tipper and I will be up really early to go to Pittsburgh Monday morning in case of bad weather. Blessings
Patti

Oh my goodness. Not good for Tipper or Lucky or you to have a mix up.

Molly simply cannot leave a cat alone, unless she is at the vets office, then none of them seem to bother her a bit, but in the house, she thinks they are her playmates and bugs them continuously. It scared me to death as I was always afraid a claw would catch an eye. As it was I use to have to go get Nova's claws unstuck from Molly's beard, they would both be putting up a ruckus that they were dying. Nova never did put a scratch on Molly, but the worry was always there. We never got another cat after Nova passed.

You certain did have an early morning and an eventful one, so I hope that you can all catch a few winks and get some rest today.

We had a very brief few minutes of snow coming down hard and then it stopped, never did stick and it's sunny and cold out. We might have a few more of those during the day, who knows.

hugs,
Sharlene and Molly Muffin

Hi Everyone:
We are having a white out and the ground is covered. Looks like a scene from a snow globe. We have about an inch so far, it is coming down hard and the wind is still 50mph. It is like a snowstorm out there that you sit inside in the warmth and enjoy. Blessings
Patti

A snowstorm, oh goodness, I hope you get to stay inside.

Oh these kitties and puppies, thank goodness everyone is ok.:):)

Patti- Marianne posted links to articles on SID verses BID on my thread.

Oh no! Animals fighting scares me! I'm glad that neither was injured.
We had flurries, not enough to stick to the ground.

Cos Cob is under gale warning and our lights have ticketed several times tonight. The pets are in Bristol with grandpa. He got flurries too.

More snow tomorrow. Not ready for this weather!

Hi Everyone:
Tipper had a good nite, but we are in the single digits outside so there will be no doggies walking this morning. Tipper is already showing me she is bored. The wind here has not let up since it started yesterday. I am taking a rest today as we have to get up at 5:00am to go to Pittsburgh to the eye Dr. I hope the roads are not bad, I hate traveling that early when there is ice and snow. It just does not have a chance to melt from the cars traveling on it too early in the morning. I brought Tipper's pillows she lays on in the house so they are toasty for her to lay on. She will have to eat her breakfast in the car, and I will have to give her the Vetoryl while traveling, that is always fun!! I try to pull off somewhere and do it, but if there isn't anywhere I will have to just do it while driving. I usually have it ready and can stuff it in the chicken while holding the wheel. Not the perfect way to go, but you do what you have to. I am praying my Steelers beat the Brown today as they have been playing like dummies all season, and Pittsburgher's are not used to seeing this from them. Blessings
Patti

I am so glad Tipper had a good night and please be careful driving tomorrow. We are to get a dusting of snow tomorrow too. I worry about Zoe walking on icy stuff.

I'm glad Tipper can still handle car rides, Zoe is impossible- about like Leslie's Squirt. She used to love to ride shot gun on my lap, not any more.

Enjoy the football game. I am trying to give our dining room a good fall cleaning before Thanksgiving. It is the one room I dont allow the dogs access to unless we are in there and I dont really clean it thoroughly, I have to cheat somewhere to find time for everything else:o:o:o:o

Enjoy your Sunday