Dr. Booth called and he was convinced :) with you all, and I will wait until the new reduced dosage pills come in. Thank you all.
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Dr. Booth called and he was convinced :) with you all, and I will wait until the new reduced dosage pills come in. Thank you all.
I'm sorry -- I missed seeing your earlier post with the test results. In this case, you really do need to stop the trilostane entirely for the moment. Here's the related portion of Dechra's dosing instructions:
So simply lowering the dose is not enough right now -- Lulu should first have a "break" from the medication in order to allow her adrenal reserves to regenerate. Also, if she continues to act "off," she really should have a blood sample drawn to check her "electrolytes" (the blood chemistries that relate to the ratio of potassium, sodium, etc.,) since steroid levels that are too low can throw off this balance.Quote:
If the ACTH stimulation test is <1.45 μg/dL (<40 nmol/L) and/or if electrolyte imbalances characteristic of hypoadrenocorticism (hyperkalemia and hyponatremia) are found, VETORYL Capsules should be temporarily discontinued until recurrence of clinical signs consistent with hyperadrenocorticism and test results return to normal (1.45-9.1 μg/dL or 40-250 nmol/L). VETORYL Capsules may then be re-introduced at a lower dose.
Marianne
P.S. We were posting at the same time. I'm really glad that Dr. Booth has agreed to hold off on the trilostane for the time being.
I want to be absolutely sure you understand -
DO NOT restart the lower dose Trilo when you get it. Lulu needs to be showing strong signs and have an ACTH that shows the cortisol is rising beyond the acceptable level BEFORE starting the new lower dose. ;)
Vets often approach Trilo (Vetoryl) thinking it is safe - it is NOT safe. It has the exact same potential risks as Lysodren and must be treated accordingly. Playing willy nilly with dosing and testing can lead to serious, permanent issues with both drugs. ;)
My Jenny went Addisonian from too much Lysodren. She hasn't had any Cushings meds since April 2012 and was on prednisone until August 2012.
Her cortisol is slowly increasing and her specialist said he doesn't want us to let it get out of control making her uncomfortable, but he wouldn't even consider giving her any cushings meds until her post #'s are over 2.0 (I'm thinking higher but we'll cross that bridge when we come to it)
glad your vet agreed to stop the trilo. I have to say it's been a nice mental break not worrying about the cushings meds for awhile.
Thanks all. I have printed some of this. And I will print the PDF too on Vetoryl.
I am thinking of calling where Dr. Booth is today, since I could just swing by the satellite office with Lulu and have her electrolytes tested. But maybe it's best to just wait and see how she does. She is peeing okay, and her stool on this morning's walk was firm.
Whew... checked in to make sure all was ok... I had to run this am. Thanks everyone for helping out where I left off. I didn't have time to search for the Dechra acth recommendations. Good job.
Dad - you are doing great. Like Leslie said - it isn't just a matter of waiting 4 days. We need to wait until the cortisol has risen to a certain level and that will require another acth test and some time. Glad Lulu is doing well. Kim
Well Lulu made it through the day. I took her with me, had to go the bank branch and then decided to go main branch, long story so will spare the details. Foggy, but went to where I completed a work project to get some money, and the owner asked if he could pay me part. I said okay as long as I could cash at his bank. Then he asked if I was going to tidy up the project like I said I could. I did for two hours, and went and walked Lulu after an hour. She peed a couple of times and went back in truck. I have water in the truck for her and stopped at convenience store to get some cheese nips for her to tide her over till home.
Now she is a bit hungrier this evening, seems more alive. She does get this way in the evenings though.
I don't know if they shipped the reduced dosage pills as they needed a new payment card and I hadn't given it to them. I might get it with a bill, but want to discuss with Dr. Booth what you all on the forum have suggested. It does make sense, I just don't want her to be ravenous again, but maybe that is her nature at times?
Whew! I am so glad the gang was here to help with LuLu's results yesterday and today. No idea How I missed yesterdays post but I swear I almost had heart failure :eek: while catching up on the goings on this evening! (we probably need a fanning yourself while swooning icon)
Worry warts indeed. :) Definitely have a chat with your vet, but I wouldn't start anything until you see that POST number come up a bit. It might even be that if she has more symptoms at night that you would consider going to a twice a day dosing, but that again, is something to talk with your vet about.
So glad that today was okay. (now no more near miss heart attacks on the forum. I'm getting older you know!) :eek: :D
Sharlene and Molly Muffin
Let us know how things are going when you can:)
Hi Addy and others. Lulu is doing fine today. She shows her hunger at the meal table. She has us trained. She is pretty good, but reminds us that she is allowed a bit of table food.
This has been day two without her trilostane. I don't know how long we should wait before she is retested, but we are taking this just one day at a time.