Flynn 11 y/o Foxie Cross - Right adrenalectomy- Good Bye Flynny We will miss you

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Originally Posted by Trish

My one thought is the time stamp on results show it was not processed by the lab till over 30 hrs after the samples were (blood and UPC) taken, not sure how that would affect the results. I have emailed the vet back to ask that, also maybe it is time to go onto liver support meds. STINK!!!!

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At room temperature, the UPC ratio did not significantly increase after 2 and 4 hours. After 12 hours at room temperature and at 4°C, the UPC ratio significantly increased. The UPC ratio did not significantly change during 3 months of storage at −20°C.

Conclusions and Clinical Relevance

The UPC ratio must be measured as soon as samples are collected. Alternatively, samples should be immediately frozen to increase their stability and minimize the risk of misclassification of proteinuria.

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Found this info at: http://avmajournals.avma.org/doi/abs...urnalCode=ajvr

Thanks for that Lori, when I next speak to the vet I will definitely be asking how they transport it. :D Flynn does not know I am worried about his tests, all he is worried about is when his next snack is coming :D:D

LOL Flynn is smart, he knows that treats are important!

Hugs,
Sharlene and Molly Muffin

Hi Trish,
I was taking a look at Flynn's lab results and wondering if you have had a chance to talk to the vet to get his explanation and insight? I understand why the liver value increases would be worrisome. I hope he has something reassuring to offer about that, and maybe it is not as significant as it appears.

Are you concerned about the UPC being up a smidge? I wonder if what Lori posted about the delay in running the test could have caused that? I didn't know about that of course, now I have questions about how my vets office handles them. I'm pretty sure they don't freeze the sample. I know they are sent to an outside lab. And you are right about the UPC, it is a quantitative test for urinary protein loss and is not affected by urine volume or concentration.

So glad to read that Flynn continues to feel so good. I am just hoping your vet has some reassuring feedback about the liver enzymes. I missed chatting over the weekend, I ended up having a lot going on. I don't like it when that happens! :rolleyes:

Hugs,
Tina and Jasper

Hi Trish-I'm no judge of the numbers but Flynn has been feeling good hasn't he? That's a good thing to keep in your head when you're thinking the numbers are not perfect.
How about a liver supplement as Sharlene mentioned...we use Denamarin which you can get online, there are probably others as well.
Trixie's liver numbers were through the roof last time we tested. She' s been on denamarin for awhile now...can only do her good. No harm in it. Hope Flynn continues to do well! :D
Barbara

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Originally Posted by Trish

UPC is up to 1.93 from 1.84 in May. It is weird as the total protein in the sample is the lowest it has been since April 2012 so I was very happy to read that, but creatinine is also low in the urine so that means the ratio increases. I cannot get my head around that test properly!! I "think" it means that the protein level may be down but the urine may be more dilute or concentrated and the ratio takes those fluctuations into account.

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The UPC ratio test is based on that the excretion of creatinine is constant for healthy animals. Over a period of time when several UPC tests are performed on a pet fluctuations of the creatinine can be seen and these flucuations can produce high or low UPC results.

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Differences in urine creatinine create confusion in clinically evaluating a single UPC result.

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Article found here: http://www.2ndchance.info/atopica-urineparameteres.pdf

Hi guys, thanks for the link Lori. It is strange that his creatinine has varied so much in the urine. It remains very stable in blood. Here are his UPC results over last year or so. As you can see this latest Protein is lowest since April last year, so that has to be good!! Tina have not spoken to vet yet about liver tests, I am not going to worry too much till we check them again in a month! Thanks for the posts everyone, I am just pleased my Flynn boy is feeling so good :D So I really think (hope) these results are a little off base, we shall see in a few weeks. xxx

6-Apr 2-Nov 22-Feb 5-Mar 2-May 22-May 10-Jul
U.TPCAL g/L 1.84 3.1 6 3 5 2.45 2.27
U.CRE umol/l 13521 18566 18194 13954 12411 11781 10380
PRCR 1.21 1.48 2.92 1.9 3.57 1.84 1.93


Hmmmm I dunno how to edit those numbers so they are readable!! It looks perfect in the preview post? but does not seem to save properly. I copied it from an excel spreadsheet so that may be the problem.

Trish:
Glad to hear some good news for once. It is nice to have a day off from worry. Hope Flynn continues to do well. Blessings
Patti

Hi Trish,
I miss you! I am thrilled that Flynny boy is feeling well, especially without TOYS!;):p He is so lucky to have you on his side. He is truly a blessed little man. Big hugs,

Good news Trish!

With Daisy's recent Trilo adjustment, the subject of numbers came up for us too and Dr. Morgan (IMS) said that she's more concerned with how she's actually feeling than the numbers.

Glad that Flynn is doing better!!!