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  #41  
Old 08-09-2017, 11:41 AM
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Default Re: My big boy Gable

Any thoughts on Gable's blood work? Next steps?
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  #42  
Old 08-09-2017, 02:39 PM
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Default Re: My big boy Gable

Do you have the results of the other bloodwork that was done? Thyroid numbers... etc etc. I'm assuming a UTI was ruled out, as well as diabetes. An xray might help but hopefully one of the other more knowledgeable folks will see this and pop in soon.

Shana
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  #43  
Old 08-09-2017, 03:08 PM
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Default Re: My big boy Gable

Gosh Joan, I'm afraid I don't have any great suggestions since the LDDS was negative. If you wanted to spend the money , I suppose you could advance to an ACTH since there is a small percentage of Cushpups that test negative on the LDDS even though Cushing's is present. However, I don't know whether you'd want to take that additional step or not.

Are all of Gable's kidney and liver results within normal range? If so, I guess the only thing I still wonder about is whether he could possibly be oversupplemented with the soloxine, since excessive thirst/urination/panting can be associated with hyperthyroidism...

Marianne
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  #44  
Old 08-09-2017, 03:09 PM
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Default Re: My big boy Gable

Yep, all that was ruled out...these are the thyroid results from the 1st test and we put him on soloxine.

T4: 0.5, ref range 0.8 - 3.5

T4: (Equilibrium Dialysis) 6, ref range 8 - 40

The second test he was still low, so we increased the soloxine.

The last one came back where it should be.
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  #45  
Old 08-09-2017, 05:13 PM
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Default Re: My big boy Gable

Well, I truly am stumped. I can't remember whether you had a full thyroid panel performed prior to starting the soloxine, or at least enough of a comprehensive panel to point to whether Gable's hypothyroidism looks to be a primary disorder or instead secondary to another condition. I think the TSH level factors into that, and I also think that Antech may have included that on an earlier comprehensive Chemistry panel. At any rate, if it's available, that may be a useful piece of info: whether or not there is some other condition that underlies the hypothyroidism. If so, that may make it seem as though advancing to an ACTH might be more worthwhile, especially since Gable's 8-hour LDDS reading was so close to the diagnostic cut-off.

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When interpreting LDDS test results, first evaluate the eight-hour post-dexamethasone administration cortisol concentration. If it is above the reference range, the dog probably has hyperadrenocorticism (false positive results may occur in dogs with nonadrenal illness). If it is within the reference range, either the dog does not have hyperadrenocorticism or there is a 5% to 10% chance that the dog has PDH. (The dog may have early pituitary disease and the pituitary gland is still responding to a pharmacologic dose of dexamethasone by decreasing ACTH production, thereby reducing serum cortisol concentrations.) In those cases, an ACTH stimulation test is warranted.

Last edited by labblab; 08-09-2017 at 05:21 PM. Reason: To reword.
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  #46  
Old 08-09-2017, 06:46 PM
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Default Re: My big boy Gable

Quote:
Originally Posted by labblab View Post
Gosh Joan, I'm afraid I don't have any great suggestions since the LDDS was negative. If you wanted to spend the money , I suppose you could advance to an ACTH since there is a small percentage of Cushpups that test negative on the LDDS even though Cushing's is present. However, I don't know whether you'd want to take that additional step or not.


Are all of Gable's kidney and liver results within normal range? If so, I guess the only thing I still wonder about is whether he could possibly be oversupplemented with the soloxine, since excessive thirst/urination/panting can be associated with hyperthyroidism...

Marianne
His panting started wayyy before the soloxine, Marianne. He only started on the soloxine a few months ago. I guess I'll just have the
x-ray done and see if it shows anything.
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Last edited by Joan2517; 08-09-2017 at 06:47 PM. Reason: His, no is...
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  #47  
Old 08-11-2017, 08:11 PM
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Default Re: My big boy Gable

Has an UTI been ruled out? Also, how about kidney or bladder stones?
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  #48  
Old 08-12-2017, 07:11 AM
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Default Re: My big boy Gable

What tests would we do to diagnose those? Would they show up on an x-ray?
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  #49  
Old 08-14-2017, 10:09 AM
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Default Re: My big boy Gable

When my Crys had urinary crystals seems like they showed up in the urine. For larger stones I would think either an xray or ultrasound would be needed to see them since they are internal and don't pass in the urine as easily as the crystals can.
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  #50  
Old 08-14-2017, 10:12 AM
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Default Re: My big boy Gable

Thanks, Leslie~
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