Canine Cushing's Information and Support Forums  

Go Back   Canine Cushing's Information and Support Forums > Helpful Resources for Owners of Cushing's Dogs

Helpful Resources for Owners of Cushing's Dogs Important information, including links to informative websites, relevant veterinary literature, how to find a Specialist and more

Closed Thread
 
Thread Tools Display Modes
  #1  
Old 05-12-2009, 04:06 AM
k9cushings k9cushings is offline
Administrator
 
Join Date: Apr 2009
Posts: 124
Default Inefficacy of selegiline ("Anipryl") in treatment of canine pituitary-dependent HAC

Inefficacy of selegiline in treatment of canine pituitary-dependent hyperadrenocorticism
JA BRADDOCK, DB CHURCH, ID ROBERTSON and ADJ WATSON
Australian Veterinary Journal, 2004;82:272-277

http://www.ncbi.nlm.nih.gov/pubmed/15181926

http://www3.interscience.wiley.com/j...45516/abstract


Full version can be seen online here:
http://web.archive.org/web/200609272...5/04050272.pdf

Quote:
Conclusions: Selegiline was confirmed as a safe drug with no important side effects in dogs but was not effective for treating canine PDH at the dose used in this study. Due to the availability of other more reliable treatments, it cannot be recommended for treating this disease in dogs. In some dogs, selegiline may have an effect in increasing the activity levels and general alertness, possibly reflecting dopaminergic effects on the brain unrelated to treatment of PDH. It is conceivable that dogs with known pars intermedia tumours could respond better to selegiline, but premortem identification of tumour location in animals is not possible at present with imaging modalities available.
Closed Thread

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -4. The time now is 11:55 AM.


Disclaimer -- The content on this site is provided for informational and educational purposes only. While we make every effort to present information that is accurate and reliable, the views expressed here are not meant to be a substitute for the advice provided by a licensed veterinarian. Please consult with your veterinarian for specific advice concerning the medical condition or treatment of your pet and before administering any medication or pursuing any course of treatment that you may read about on this site.

The views and opinions expressed by contributors to this forum are strictly their own and do not necessarily reflect the opinions and views of the owners, administrators, or moderators of this forum and the k9cushings.com website.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2017, vBulletin Solutions, Inc.