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Thread: New to Site - American Eskimo - Cushings????

  1. #11
    Join Date
    Apr 2009
    Location
    Georgia
    Posts
    13,250

    Default Re: New to Site - American Eskimo - Cushings????

    Under the circumstances, I think your internist’s suggestion to have Yukie’s ACTH analyzed by the University of Tennessee makes sense. Their lab is able to measure the effect of the stimulating agent on a number of adrenal hormones in addition to cortisol. As it turns out, elevations in some of these other hormones can result in many of the same symptoms as are caused by elevated cortisol. Sometimes this occurs even when cortisol levels are normal or only mildly elevated, and therefore treatment other than Vetoryl may be recommended. Since Yukon reacted so poorly to the Vetoryl, this additional information may be useful.

    When elevations in other adrenal hormones cause problems, the diagnosis that may be given is “Atypical Cushing’s.” You can read more about this diagnosis here. It can be fairly heavy reading, and unfortunately a lot of question marks yet remain about the cause, significance and treatment of elevated adrenal hormones. But this info may help shed some light on the testing that the internist is suggesting.

    http://www.k9cushings.com/forum/show...Hyperestrinism

    I do think the results of the ACTH will be useful, especially since this will be the first ACTH for Yukon. In terms of elevated cortisol, the ACTH is less vulnerable to “false positives” than is the LDDS because it is not quite as reactive to the presence of other physical illnesses or stresses. So overall, I think this is a good plan for Yukon.

    To me, the only questionable aspect of your internist’s plan is the UCCR if the urine sample was obtained in the office. That test is highly vulnerable to stress so it is generally recommended that the sample be obtained at home when the dog is calm. But perhaps your vet thought, what the heck, let’s go ahead and see how it turns out anyway.

    So, in summary, do keep us informed. But I do think the ACTH may be useful.

    Marianne

  2. #12
    Join Date
    May 2018
    Posts
    8

    Default Re: New to Site - American Eskimo - Cushings????

    Thank you so much Marianne for the explanation - maybe we will be able to determine what is really going on finally. Also, the UCCR test is being ran from a first morning urine that I collected on his walk when we got up. One thing I have learned is that it is better to bring the urine sample even if they don't use it

    I will keep you informed of Yukon's travels - thanks again for the information.

  3. #13
    Join Date
    Apr 2009
    Location
    Georgia
    Posts
    13,250

    Default Re: New to Site - American Eskimo - Cushings????

    Quote Originally Posted by YukiesMom View Post
    Also, the UCCR test is being ran from a first morning urine that I collected on his walk when we got up. One thing I have learned is that it is better to bring the urine sample even if they don't use it
    Perfect! Then the results from the urine sample will definitely be interesting, too.

    Good job, mom!!!

  4. #14
    Join Date
    May 2018
    Posts
    8

    Default Re: New to Site - American Eskimo - Cushings????

    I am trying. This is very complicated. I just wish someone could come to a diagnosis. I have been saying for the last two weeks I want to put him on lignans and melatonin. I have been reading about this venue for atypical cushings.

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