Re: Is it cushings or not with our blue
Blue is on 120mg and went from 28 post cortisol to 3.5 pre and post? in 30 days on 120. And blue weighs 95lbs, so my concern here is that the dosage is too much, that is alot very quickly. 3.5 pre and post means that no additional cortisol was released from the adrenal gland after the ACTH injection.
So, here is what I would do if in your shoes. Based on a the way testing is now being done in Europe and which is actually considered to be a more accurate method of determining how a dog is reacting on the medication. They are testing cortisol levels, with a simple blood draw prior to the trilostane being given to see what the level is. It cost less and is accurate.
This was posted to another member
Just within the last couple of weeks, those of us in the U.S. have learned that many vets in the U.K. and Europe have shifted away from using ACTH stimulation tests to monitor trilostane treatment unless there is a worry that a dog’s cortisol may have dropped too low. Instead, they are simply measuring resting cortisol right before the next dose of trilostane is due to be given. New research supports the notion that this actually gives better guidance re: the need for dosing increases, and it’s certainly a heck of a lot cheaper. Take a look at this link and the monitoring flowchart that’s included. Your vet may be very interested in this info, as well, and might be willing to investigate it further on your behalf.
http://www.k9cushings.com/forum/show...=1252#post1252
So I'd print that out, take it to the vet and say just to ease my mind, can we please just check the cortisol before she gets her med one day in a week or two.
Sharlene and the late great diva - Molly muffin (always missed and never forgotten)