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Thread: Cushing's - Treatment

  1. #11

    Default Cushing's - Treatment

    Comparing therapies for canine hyperadrenocorticism
    By: Johnny D. Hoskins, DVM, PhD, Dipl. ACVIM
    DVM Newsmagazine, Oct 1, 2007

    page 1 of DVM Newsmagazine article:
    http://www.dvmnews.com/dvm/Small+ani.../detail/460965

    or http://veterinarynews.dvm360.com/dvm.../detail/460965

    page 2 of DVM Newsmagazine article:
    http://www.dvmnews.com/dvm/article/a...date=&pageID=2

    or http://veterinarynews.dvm360.com/dvm...date=&pageID=2

    page 3 of DVM Newsmagazine article:
    http://www.dvmnews.com/dvm/article/a...date=&pageID=3

    or http://veterinarynews.dvm360.com/dvm...date=&pageID=3

    *Thanks to Glynda for the links

  2. #12

    Default Cushing's - Treatment

    Inefficacy of selegiline in treatment of canine pituitary-dependent hyperadrenocorticism
    JA BRADDOCK, DB CHURCH, ID ROBERTSON and ADJ WATSON
    Australian Veterinary Journal, 2004;82:272-277

    http://www.ncbi.nlm.nih.gov/pubmed/15181926

    http://www3.interscience.wiley.com/j...45516/abstract


    Full version can be seen online here:
    http://web.archive.org/web/200609272...5/04050272.pdf

    Conclusions: Selegiline was confirmed as a safe drug with no important side effects in dogs but was not effective for treating canine PDH at the dose used in this study. Due to the availability of other more reliable treatments, it cannot be recommended for treating this disease in dogs. In some dogs, selegiline may have an effect in increasing the activity levels and general alertness, possibly reflecting dopaminergic effects on the brain unrelated to treatment of PDH. It is conceivable that dogs with known pars intermedia tumours could respond better to selegiline, but premortem identification of tumour location in animals is not possible at present with imaging modalities available.

  3. #13

    Default Cushing's - Treatment

    How I Treat Pituitary Dependant Hyperadrenocorticism
    David B. Church, BVSc, PhD, MACVSc, MRCVs, ILTM
    Department of Veterinary Clinical Sciences, The Royal Veterinary College
    North Mymms, Hatfield, Hertfordshire, UK

    http://www.vin.com/proceedings/Proce...3874&O=Generic

  4. #14

    Default Cushing's - Treatment

    "What are your trilostane dosing and monitoring recommendations in dogs with hyperadrenocorticism?"

    "Should I switch treatment from mitotane to trilostane in dogs being treated for hyperadrenocorticism?"

    Video Presentation By: David S. Bruyette, DVM, DACVIM
    VETERINARY MEDICINE, Feb 1, 2009

    http://veterinarymedicine.dvm360.com.../detail/567360

  5. #15

    Default Cushing's - Treatment

    Here is a link to the full text of this 2011 research study published by Dr. Edward C. Feldman of University of California at Davis:

    "Evaluation of twice-daily lower-dose trilostane treatment administered orally in dogs with naturally occurring hyperadrenocorticism"


    Here is a link to a more streamlined summary of Dr. Feldman's key reasearch findings:

    http://veterinarymedicine.dvm360.com/vetmed/Medicine/Hot-Literature-Hyperadrenocorticism-Is-lower-dose-/ArticleStandard/Article/detail/743086

  6. #16
    Join Date
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    Default Cushing's - Treatment

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